| Identification | More | [Name]
Sodium sulfadiazine | [CAS]
547-32-0 | [Synonyms]
4-AMINO-N-[2-PYRIMIDINYL]BENZENESULFONAMIDE SODIUM SALT
PERFRINGENS SUPPLEMENT I
SODIUM 4-AMINO-N-PYRIMIDIN-2-YL-BENZENESULFONAMIDE
SODIUM SULFADIAZINE
SPS AGAR SUPPLEMENT
SULFADIAZINE SODIUM
SULFADIAZINE SODIUM SALT
(n(sup1)-2-pyrimidinylsulfanilamido)-sodiu
2-sulfanilamidopyrimidinesodiumsalt
4-amino-n-2-pyrimidinyl-benzenesulfonamidmonosodiumsalt
monosodium2-sulfanilamidopyrimidine
n(sup1)-2-pyrimidinylsulfanilamidemonosodiumsalt
n(sup1)-2-pyrimidinyl-sulfanilamidmonosodiumsalt
n(sup1)-2-pyrimidinyl-sulfanilamidn(sup1)-sodiumderiv
sodiumsulfapyrimidine
solublesulfadiazine
sulfadiazine sodium sigmaultra
PERFRINGENS SUPPLEMENT I FOR MICRO-BIOL
SULFADIAZINESODIUM,USP
SULFADIAZINE SODIUM (SD-NA) | [EINECS(EC#)]
208-919-0 | [Molecular Formula]
C10H9N4NaO2S | [MDL Number]
MFCD00067333 | [Molecular Weight]
272.26 | [MOL File]
547-32-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
>300°C | [storage temp. ]
2-8°C
| [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [color ]
White to Off-White | [BRN ]
4068213 | [Stability:]
Hygroscopic | [Major Application]
forensics and toxicology
pharmaceutical (small molecule) | [InChI]
InChI=1S/C10H10N4O2S.Na.H/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;;/h1-7H,11H2,(H,12,13,14);; | [InChIKey]
JLDCNMJPBBKAHH-UHFFFAOYSA-N | [SMILES]
S(C1C=CC(N)=CC=1)(=O)(=O)NC1=NC=CC=N1.[NaH] | [CAS DataBase Reference]
547-32-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R42/43:May cause sensitization by inhalation and skin contact . | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
3249 | [WGK Germany ]
3
| [RTECS ]
WP2000000
| [F ]
10-21 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Chronic 2
Eye Irrit. 2
Skin Irrit. 2 |
| Hazard Information | Back Directory | [Chemical Properties]
White to yellow crystalline powder | [Uses]
Sulfadiazine Sodium Salt can be used as reactant/reagent in preparation and crystal structure of aminophenyl sulfonamide tetrahalides, hydrochloride and hydrobromide cocrystals with iodine. | [General Description]
Soluble sulfadiazine is an anhydrous, white, colorless, crystallinepowder soluble in water (1:2) and slightly soluble inalcohol. Its water solutions are alkaline (pH 9–10) and absorbcarbon dioxide from the air, with precipitation of sulfadiazine.It is administered as a 5% solution in sterile waterintravenously for patients requiring an immediately highblood level of the sulfonamide. | [in vivo]
In this study, the effectiveness of Sulfadiazine sodium and Pyrimetamine for the treatment of mice during acute infection with different atypical T. gondii strains was evaluated. Swiss mice were infected with seven T. gondii strainsl. The infected mice were treated with 10-640?mg/kg per day of Sulfadiazine sodium, 3-200?mg/kg per day of Pyrimetamine, or a combination of both drugs with a lower dosage. A descriptive analysis was used to assess the association between susceptibility to sodium and/or Pyrimetamine and the genotype. The TgCTBr4 and TgCTBr17 strains (genotype 108) presented lower susceptibility to sodium or Pyrimetamine treatment. The TgCTBr1 and TgCTBr25 strains (genotype 206) presented similar susceptibility to PYR but not sodium treatment. The TgCTBr9 strain (genotype 11) was the only strain with high susceptibility to treatment with both drugs [1]. | [IC 50]
Toxoplasma |
|
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
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