| Identification | Back Directory | [Name]
disodium 1,3-dihydro-7-methyl-2-oxo-2H-indole-3,3-diylbis(p-phenylene) bis(sulphate) | [CAS]
54935-04-5 | [Synonyms]
sulisatin
Sulisatin sodium
Sulisatin disodium salt
1,3-Dihydro-7-methyl-3,3-bis[4-(sodiosulfooxy)phenyl]-2H-indol-2-one
Sodium (7-methyl-2-oxoindoline-3,3-diyl)bis(4,1-phenylene) bis(sulfate)
disodium 1,3-dihydro-7-methyl-2-oxo-2H-indole-3,3-diylbis(p-phenylene) bis(sulphate) | [EINECS(EC#)]
259-399-7 | [Molecular Formula]
C21H17NO9S2.2Na | [MDL Number]
MFCD01747123 | [MOL File]
54935-04-5.mol |
| Hazard Information | Back Directory | [Uses]
Sulisatin (DAN-603) disodium is an anionic diarrhea-promoting compound. During oral administration, Sulisatin disodium is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon[1]. | [References]
[1] Mayur M Patel. Cutting-edge technologies in colon-targeted drug delivery systems. Expert Opin Drug Deliv. 2011 Oct;8(10):1247-58. DOI:10.1517/17425247.2011.597739 |
|
|