| Identification | Back Directory | [Name]
4',6-Dimethoxy-7-hydroxyisoflavone | [CAS]
550-79-8 | [Synonyms]
AFROMOSIN
Afrormosin
Aids027673
Aids-027673
Afrormosine
7-HYDROXY-4',6-DIMETHOXYISOFLAVONE
4',6-Dimethoxy-7-hydroxyisoflavone
7-Hydroxy-6,4'-dimethoxyisoflavone
Astragalus Metabolite 7 (Afromosin)
6,4'-Dimethoxy-7-hydroxyisoflavone (Afrormosin)
6,4'- Dimethoxy -7- hydroxy Isoflavone {or }AFRORMOSIN
7-Hydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one
7-Hydroxy-3-(4-methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
7-Hydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-methoxyphenyl)-6-methoxy-
4H-1-Benzopyran-4-one, 7-hydroxy-6-methoxy-3-(4-methoxyphenyl)- | [Molecular Formula]
C17H14O5 | [MDL Number]
MFCD02113858 | [MOL File]
550-79-8.mol | [Molecular Weight]
298.29 |
| Chemical Properties | Back Directory | [Melting point ]
228-229 °C | [Boiling point ]
516.0±50.0 °C(Predicted) | [density ]
1.321±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
7.01±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Afromosin is an isoflavone, that can be isolated from Millettia dielsiana Harms. Afromosin exhibits remarkable tumor inhibitory effects[1][2]. | [Definition]
ChEBI: A methoxyisoflavone that is isoflavone substituted by methoxy groups at positions 6 and 4' and a hydroxy group at position 7. | [References]
[1] Gong T, et al. Novel benzil and isoflavone derivatives from Millettia dielsiana. Planta Med. 2009 Feb;75(3):236-42. DOI:10.1055/s-0028-1112203
[2] Konoshima T, et al. Anti-tumor-promoting activities of afromosin and soyasaponin I isolated from Wistaria brachybotrys. J Nat Prod. 1992 Dec;55(12):1776-8. DOI:10.1021/np50090a011 |
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