ChemicalBook--->CAS DataBase List--->552-38-5

552-38-5

552-38-5 Structure

552-38-5 Structure
IdentificationMore
[Name]

LITHIUM SALICYLATE
[CAS]

552-38-5
[Synonyms]

LITHIUM SALICYLATE
SALICYLIC ACID LITHIUM SALT
2-hydroxy-benzoicacimonolithiumsalt
o-Hydroxybenzoic acid lithium salt
LITHIUM SALICYLATE, 99.99%
Lithiumsalicylate,tech.
Lithiumsalicylat
Benzoic acid, 2-hydroxy-, monolithium salt
2-Hydroxybenzoic acid lithium salt
[EINECS(EC#)]

209-011-7
[Molecular Formula]

C7H5LiO3
[MDL Number]

MFCD00045813
[Molecular Weight]

144.05
[MOL File]

552-38-5.mol
Chemical PropertiesBack Directory
[Melting point ]

>350 °C (lit.)
[density ]

1.428[at 20℃]
[form ]

Powder
[Water Solubility ]

Soluble in water
[BRN ]

3732791
[CAS DataBase Reference]

552-38-5(CAS DataBase Reference)
[EPA Substance Registry System]

Benzoic acid, 2-hydroxy-, monolithium salt (552-38-5)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

R22:Harmful if swallowed.
R36/38:Irritating to eyes and skin .
[Safety Statements ]

S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

1
[F ]

3-10
[TSCA ]

Yes
Questions And AnswerBack Directory
[Description]

Lithium salicylate is the lithium salt of salicylate, which is a kind of organic acid. Lithium salicylate may be a good alternative for treating bipolar disorder and other neuropsychiatric conditions as it was recently found that oral lithium salicylate was able to produce steady lithium levels for up to 48 hours in rats – without the toxic side effects typically linked with the rapid absorption of current FDA-approved lithium carbonate. It is also proposed that lithium salicylate is most effective drug in reducing self-harm and suicide.
The therapeutic effect of lithium salicylate allows for its application in diuretics. In addition, with the aid of its catalysis effect, this chemical can be employed as the catalysts for chemiluminescent system or trimer catalyst for aliphatic and aromatic isocyanates.
[Sources]

https://www.redorbit.com/news/health/1113093183/biploar-disorder-lithium-therapy-sodium-based-better-031214/
https://www.theguardian.com/society/2016/aug/14/lithium-should-be-more-widely-used-for-bipolar-disorder-researchers-say
https://www.sdrugs.com/?c=drug&s=lithium%20salicylate
Junquera, E.; Pena, L.; Aicart, E., Binding of sodium salicylate by beta-cyclodextrin or 2,6-di-O-methyl-beta-cyclodextrin in aqueous solution. J. Pharm. Sci. 1998, 87, 86-90.
Herbert, P. R.; Joseph, H. J., Chemiluminescent system catalysts. United Sates Patent 4626383 1986.
W.E., S.; H.T., K.; T., H., Trimer catalyst for aliphatic and aromatic isocyanates. United Sates Patent 5905151 1999.
Spectrum DetailBack Directory
[Spectrum Detail]

LITHIUM SALICYLATE(552-38-5)1HNMR
LITHIUM SALICYLATE(552-38-5)13CNMR
LITHIUM SALICYLATE(552-38-5)IR1
LITHIUM SALICYLATE(552-38-5)IR2
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

Lithium salicylate, tech.(552-38-5)
[Sigma Aldrich]

552-38-5(sigmaaldrich)
[TCI AMERICA]

Salicylic Acid Lithium Salt,>95.0%(T)(552-38-5)
Hazard InformationBack Directory
[Flammability and Explosibility]

Notclassified
[Purification Methods]

Recrystallise it from EtOH (2mL/g) by partial evaporation. [Beilstein 10 H 59, 10 II 32, 10 III 93, 10 IV 126.]
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