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552-58-9

552-58-9 Structure

552-58-9 Structure
IdentificationMore
[Name]

ERIODICTYOL
[CAS]

552-58-9
[Synonyms]

2-[3,4-DIHYDROXYPHENYL]2,3-DIHYDRO-5,7-DIHYDROXY-4H-1BENZOPYRAN-4-ONE
3',4',5,7-TETRAHYDROXYFLAVANONE
5,7,3',4'-TETRAHYDROXYFLAVANONE
ERIODICTYOL
(S)-3',4',5,7-TETRAHYDROXYFLAVANONE
(S)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone
(2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-chroman-4-one
ERIODICTYOL(SH)
ERIODICTIOL
ERIODICTYOL hplc
ERIODICTYOL WITH HPLC
(2S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one
(2S)-2α-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one
(S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one
[EINECS(EC#)]

209-016-4
[Molecular Formula]

C15H12O6
[MDL Number]

MFCD00135890
[Molecular Weight]

288.25
[MOL File]

552-58-9.mol
Chemical PropertiesBack Directory
[Melting point ]

270°C
[Boiling point ]

625.2±55.0 °C(Predicted)
[density ]

1.586±0.06 g/cm3(Predicted)
[FEMA ]

4715 | 2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-4-CHROMANON
[storage temp. ]

2-8°C
[solubility ]

DMSO (Slightly), Methanol (Very Slightly)
[form ]

neat
[pka]

7.49±0.40(Predicted)
[color ]

White to Pale Beige
[Water Solubility ]

70mg/L(20 ºC)
[JECFA Number]

2172
[BRN ]

5104930
[Stability:]

Hygroscopic
[InChI]

1S/C15H12O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-5,13,16-19H,6H2/t13-/m0/s1
[InChIKey]

SBHXYTNGIZCORC-ZDUSSCGKSA-N
[SMILES]

Oc1cc(O)c2C(=O)C[C@H](Oc2c1)c3ccc(O)c(O)c3
[CAS DataBase Reference]

552-58-9(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
[WGK Germany ]

3
[HS Code ]

29329990
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Chemical Properties]

It is easily soluble in methanol, slightly soluble in boiling water, hot ethanol, ether and glacial acetic acid, and soluble in dilute alkali.
[Uses]

Eriodictyol is used in biological studies as natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation. Eriodictyl is extracted from Yerba santa, an herb. The leaf is used to make medicine.Yerba santa is used for respiratory conditions including coughs, colds, tuberculosis, asthma, and chronic bronchitis. It is also used for fever and dry mouth. Some people use it to relieve muscle spasms, to loosen phlegm, and as a tonic.
[Definition]

ChEBI: A tetrahydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7, 3' and 4' respectively.
[Biochem/physiol Actions]

The flavanone eriodictyol is a metabolite in the flavonoid biosynthesis pathway. Eriodictyol has anti-inflammatory and antioxidant activities and taste-modifying properties; it is extracted from plants such as Eriodictyon californicum, the twigs of Millettia duchesnei, in Eupatorium arnottianum, lemons and as glycoside in rose hips (Rosa canina).
[in vivo]

Eriodictyol shows protective effect against LPS-induced acute lung injury (ALI). Eriodictyol (30 mg/kg, p.o.) decreases the production of inflammatory cytokines, elevates survival rate, and decreases oxidative stress levels in LPS-induced ALI mice. Eriodictyol inhibits MPO activity and inflammatory neutrophil accumulation in the lung tissues. Eriodictyol treatment also enhances Trx1 expression by upregulating the Nrf2 expression in lung tissues[1].

Spectrum DetailBack Directory
[Spectrum Detail]

ERIODICTYOL(552-58-9)MS
ERIODICTYOL(552-58-9)1HNMR
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