| Identification | More | [Name]
5-Methyl-2'-deoxycytidine | [CAS]
838-07-3 | [Synonyms]
2'-DEOXY-5-METHYLCYTIDINE
4-AMINO-1-[(2R,4S,5R)-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-METHYL-PYRIMIDIN-2-ONE
5-METHYL-2'-DEOXYCYTIDINE
5-METHYL-2'-DEXOYCYTIDINE
5-METHYL-DC
2’-deoxy-5-methyl-cytidin
5-methyldeoxycytidine
Cytidine, 2'-deoxy-5-methyl-
2'-Deoxy-5-methyl-D-cytidine
4-amino-1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one
2''-DEOXY-5-METHYLCYTIDINE (5-METHYL-2''-DEOXYCYTIDINE)
1-(2-Deoxy-beta-D-ribofuranosyl)-5-methylcytosine | [EINECS(EC#)]
212-655-1 | [Molecular Formula]
C10H15N3O4 | [MDL Number]
MFCD00006549 | [Molecular Weight]
241.24 | [MOL File]
838-07-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
217-219 °C(lit.)
| [Boiling point ]
492.8±55.0 °C(Predicted) | [density ]
1?+-.0.1 g/cm3(Predicted) | [refractive index ]
44 ° (C=1.4, H2O) | [storage temp. ]
−20°C
| [solubility ]
DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly) | [form ]
Powder | [pka]
pK1:4.33 (25°C) | [color ]
White to Off-white | [Water Solubility ]
Soluble in water. | [Stability:]
Hygroscopic | [CAS DataBase Reference]
838-07-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
HA3860000
| [HS Code ]
29389090 |
| Hazard Information | Back Directory | [Description]
5-Methyl-2'-deoxycytidine is a nucleoside analogue that inhibits the synthesis of DNA. 5-Methyl-2'-deoxycytidine prevents methylation of guanine, which disrupts the binding of guanine nucleotide-binding proteins to the dna template and prevents polymerase chain reactions. 2'-Deoxy-5-methylcytidine is also a methyltransferase inhibitor, which means it blocks the enzyme responsible for adding methyl groups to cytosine molecules. | [Chemical Properties]
White Solid | [Uses]
5-Methyl-2'-deoxycytidine is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo DNA methylation. It has been used in epigenetics research to investigate the dynamics of DNA methylation pattern in the control of gene expression. | [Uses]
A Cytidine (C998300) analog and also an isostere of Thymidine (T412000). | [Definition]
ChEBI: 5-methyl-2'-deoxycytidine is a 2'-deoxycytidine. | [storage]
Store at -20°C |
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