| Identification | More | [Name]
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE | [CAS]
5617-70-9 | [Synonyms]
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE
CYCL-ISOPROPYLIDENE CYCLOPROPANE-1,1-DICARBOXYLATE
CYCLOPROPANE-1,1-DICARBOXYLIC ACID CYCL-ISOPROPYLIDENE ESTER
CYCLOPROPANE-1,1-DICARBOXYLIC ACID CYCLOISOPROPYLIDENE ESTER
1,1-Cyclopropanedicarboxylic acid cycl-isopropylidene ester~cycl-Isopropylidene 1,1-cyclopropanedicarboxylate
CYCLOPROPYL MELDRUM'S ACID
Danishefsky's reagent
CYCLOPROPANE-1,1-DICARBOXYLIC ACID CYCL-ISOPRYLIDENE ESTER
Cyclopropane-1,1-dicarboxylic acid cyclic-isopropylidene ester
1,1-Cyclopropanedicarboxylic acid cyclic isopropylidene ester, 6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione
cyclic Isopropylidene 1,1-cyclopropanedicarboxylate
2,2-Dimethylspiro[1,3-dioxane-5,1'-cyclopropane]-4,6-dione
3,3-Dimethyl-2,4-dioxaspiro[5.2]octane-1,5-dione
5,7-Dioxa-6,6-dimethylspiro[2.5]octane-4,8-dione
Cyclopropane-1,1-dicarboxylic acid isopropylidene ester | [EINECS(EC#)]
227-044-5 | [Molecular Formula]
C8H10O4 | [MDL Number]
MFCD00042796 | [Molecular Weight]
170.16 | [MOL File]
5617-70-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
63-65 °C(lit.) | [Boiling point ]
396.8±35.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMF: soluble(lit.) | [form ]
Solid | [color ]
White to Off-White | [BRN ]
1241835 | [InChI]
InChI=1S/C8H10O4/c1-7(2)11-5(9)8(3-4-8)6(10)12-7/h3-4H2,1-2H3 | [InChIKey]
AXJVPXNVESYGDT-UHFFFAOYSA-N | [SMILES]
C1C2(C(=O)OC(C)(C)OC2=O)C1 | [CAS DataBase Reference]
5617-70-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
2932209090 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Uses]
6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism). | [Synthesis Reference(s)]
Organic Syntheses, Coll. Vol. 7, p. 411, 1990
The Journal of Organic Chemistry, 40, p. 2969, 1975 DOI: 10.1021/jo00908a030 |
| Spectrum Detail | Back Directory | [Spectrum Detail]
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(5617-70-9)MS
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(5617-70-9)1HNMR
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(5617-70-9)13CNMR
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(5617-70-9)IR1
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(5617-70-9)IR2
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