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Femoxetine hydrochloride is a serotonin (5-HT) inhibitor with antidepressant properties. Femoxetine hydrochloride increases serotonin levels in the brain by preventing serotonin from being reabsorbed by nerve cells, resulting in increased concentrations of the neurotransmitter in the synaptic gap, which enhances serotonin signaling. Femoxetine hydrochloride can be used to study the role of serotonin in depression and other emotional disorders, and how 5-HT reuptake inhibitors affect mood and behavior[1][2]. | [References]
[1] Bechgaard E, et al. Hepatic elimination of femoxetine in pig[J]. Acta Pharmacologica et Toxicologica, 1983, 52(1): 1-7. DOI:10.1111/j.1600-0773.1983.tb01067.x
[2] Lund J, et al. Pharmacokinetics of femoxetine in man[J]. Acta Pharmacologica et Toxicologica, 1979, 44(3): 177-184. DOI:10.1111/j.1600-0773.1979.tb02314.x |
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