| Identification | Back Directory | [Name]
8-O-acetyl shanzhiside methyl ester | [CAS]
57420-46-9 | [Synonyms]
ND01
Barlerin
UMbroside
8-O-Acetyl shanzhiside methyl
8-Acetylshanzhiside Methyl ester
O-Acetyl Shanzhiside Methyl Ester, 8-
8-O-Acetyl shanzhiside methyl ester, >98%
8-O-Acetyl shanzhiside methyl ester, 98%, from Lamiophlomis rotata (Benth. ex Hook.f.) Kud
1α-(β-D-Glucopyranosyloxy)-7α-acetoxy-5α-hydroxy-7-methyl-1,4aα,5,6,7,7aα-hexahydrocyclopenta[c]pyran-4-carboxylic acid methyl ester
7α-Acetoxy-1α-(β-D-glucopyranosyloxy)-1,4aα,5,6,7,7aα-hexahydro-5α-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic acid methyl ester
(1S)-1α-(β-D-Glucopyranosyloxy)-5α-hydroxy-7α-acetoxy-7-methyl-1,4aα,5,6,7,7aα-hexahydrocyclopenta[c]pyran-4-carboxylic acid methyl ester
methyl (1S,4aS,5R,7S,7aS)-7-(acetyloxy)-1-(beta-D-glucopyranosyloxy)-5-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate
Cyclopenta[c]pyran-4-carboxylic acid, 7-(acetyloxy)-1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-5-hydroxy-7-methyl-, methyl ester, (1S,4aS,5R,7S,7aS)-
methyl (1S,4aS,5R,7S,7aS)-7-acetyloxy-5-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylate | [Molecular Formula]
C19H28O12 | [MDL Number]
MFCD15071141 | [MOL File]
57420-46-9.mol | [Molecular Weight]
448.42 |
| Chemical Properties | Back Directory | [Boiling point ]
634.2±55.0 °C(Predicted) | [density ]
1.52 | [storage temp. ]
-20°C | [solubility ]
Soluble in methan | [form ]
powder | [pka]
12.80±0.70(Predicted) | [color ]
White | [Major Application]
food and beverages | [InChIKey]
ARFRZOLTIRQFCI-NGQYDJQZSA-N | [SMILES]
O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@@H]2OC=C([C@@H]3[C@H]2[C@](C[C@H]3O)(OC(=O)C)C)C(=O)OC |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white crystalline powder, easily soluble in methanol and ethanol, derived from unique flavor. | [Uses]
8-O-acetyl shanzhiside methyl ester can be used for content determination, identification and pharmacological experiments, etc. It can activate congestion, relieve pain and stop bleeding. | [in vitro]
Treatment of SH-SY5Y cells with 8-O-Acetyl shanzhiside methyl ester blocks TNF-α-induced nuclear transcription factor κB (NF-κB) activation and decreases high-mobility group box-1 ( HMGB-1) expression . Treatment of H9c2 cells with it 9 μM blocks TNF-α-induced NF-κB phosphorylation by blocking High-mobility group box1 (HMGB1) expression. | [in vivo]
8-O-Acetyl shanzhiside methyl ester significantly promotes angiogenesis in the ischaemic brain and improves functional outcome after stroke. It also significantly increases vascularization compared with vehicle treatment. 8-O-Acetyl shanzhiside methyl ester significantly shortens capillary blood clotting time and reduces blood loss volume, but does not influence mice activated partial thromboplastin time , prothrombin time or thrombin time. |
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