| Identification | Back Directory | [Name]
sphondin | [CAS]
483-66-9 | [Synonyms]
Sfondin
sphondin
6-Methoxy-2H-furo[2,3-h][1]benzopyran-2-one
6-Methoxy-2H-furo[2,3-h]-1-benzopyran-2-one
2H-Furo(2,3-h)-1-benzopyran-2-one, 6-Methoxy- | [Molecular Formula]
C12H8O4 | [MDL Number]
MFCD00597230 | [MOL File]
483-66-9.mol | [Molecular Weight]
216.19 |
| Chemical Properties | Back Directory | [Melting point ]
189-191 °C | [Boiling point ]
413.0±45.0 °C(Predicted) | [density ]
1.368±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [form ]
Solid | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white needle-like crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Oxtail Duhuo. | [Uses]
Sphondin has an Analgesic, anti-inflammatory, anti-allergic, smooth muscle spasmolytic effect. | [Definition]
ChEBI: Sphondin is a furanocoumarin. | [Biological Activity]
Sphondin, isolated from Heracleum laciniatum, has inhibitory effects on IL-1β-induced increases in COX-2 protein and PGE2 release levels in A549 cells. | [in vitro]
Pretreatment of A549 cells with Sphondin (10-50 μM) concentration-dependently attenuates IL-1β-induced COX-2 protein expression and PGE 2 release. | [target]
|
|
|