| Identification | Back Directory | [Name]
Bixafen| | [CAS]
581809-46-3 | [Synonyms]
Bixafen@1000 μg/mL in Acetonitrile Bixafen Standard@100 μg/mL in Acetonitrile N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-... N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide N-(3',4'-Dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide 1H-Pyrazole-4-carboxamide, N-(3',4'-dichloro-5-fluoro[1,1'-biphenyl]-2-yl)-3-(difluoromethyl)-1-methyl- | [Molecular Formula]
C18H12Cl2F3N3O | [MDL Number]
MFCD16652583 | [MOL File]
581809-46-3.mol | [Molecular Weight]
414.209 |
| Safety Data | Back Directory | [Symbol(GHS) ]
 GHS09 | [Signal word ]
Warning | [Hazard statements ]
H400 | [Precautionary statements ]
P273 | [Hazard Codes ]
N | [Risk Statements ]
50/53 | [Safety Statements ]
60-61 | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
2 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Aquatic Acute 1 |
| Hazard Information | Back Directory | [Description]
Bixafen is a cereal fungicide used in the control of stem and leaf diseases. It has a low aqueous solubility and is not volatile. This substance can be very environmentally persistent but is not expected, based on its physico-chemical properties, to leach to groundwater. It is highly toxic to fish, moderately toxic to birds, aquatic invertebrates and algae but has a low toxicity to honeybees. Bixafen has a low mammalian toxicity via the oral route and is a probable reproduction/developmental toxin. | [Chemical Properties]
Bifenpyrad is white powder, melting point 142.9°C, vapor pressure 4.6×103mPa(20°C), K . lgP =3.3(20℃), relative density 1.51(20℃), solubility in water 0.49mg/L(pH 7,20℃). Stable to light and water (pH 4~9). | [Uses]
Bixafen is a novel succinate dehydrogenase inhibitor fungicide found in vegetables and fruits. | [Definition]
ChEBI: An aromatic amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 3',4'-dichloro-5-fluorobiphenyl-2-amine. A fungicide for use in cereals for key stem and leaf disease co
trol including strobilurin-resistant septoria. | [Production Methods]
Bixafen is commercially synthesised by coupling a substituted pyrazole carboxylic acid with a halogenated biphenyl amine. The industrial production of bixafen begins with the preparation of 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid, which serves as the core scaffold. This intermediate is then reacted with 3',4'-dichloro-5-fluoro-2-aminobiphenyl through an amide bond formation, yielding the active compound. | [Mechanism of action]
Succinate DeHydrogenase Inhibitor. | [Pesticide Type]
Fungicide |
|
|