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5836-29-3

5836-29-3 Structure

5836-29-3 Structure
IdentificationMore
[Name]

Coumatetralyl
[CAS]

5836-29-3
[Synonyms]

4-HYDROXY-3-(1,2,3,4-TETRAHYDRO-1-NAPHTALENYL)-2H-1-BENZOPYRAN-2-ONE
4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)coumarin
4-HYDROXY-3-(1,2,3,4-TETRAHYDRO-1-NAPHTHYL) COUMARINE
Cou matctralyl
COUMATETRALYL
RACUMIN
RECUMIN(R)
3-(1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxycumarin
3-(1,2,3,4-tetrahydro-1-naphtyl)-4-hydroxycoumarine
3-(1,2,3,4-tetrahydro-1-naphtyl)-4-hydroxycoumarine(french)
3-(alpha-tetral)-4-oxycoumarin
3-(alpha-tetralyl)-4-hydroxycoumarin
3-(d-tetralyl)-4-hydroxycoumarin
4-hydroxy-3-(1,2,3,4-tetrahydro-1-naftyl)-cumarine
4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-2h-1-benzopyran-2-on
4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-2H-1-Benzopyran-2-one
4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)-coumari
4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)-cumarin
4-idrossi-3-(1,2,3,4-tetraidro-1-naftil)-cumarina
bay25634
[EINECS(EC#)]

227-424-0
[Molecular Formula]

C19H16O3
[MDL Number]

MFCD00078644
[Molecular Weight]

292.33
[MOL File]

5836-29-3.mol
Chemical PropertiesBack Directory
[Appearance]

Coumatetralyl is a yellowish-white, crystalline solid.
[Melting point ]

172-176 °C
[Boiling point ]

374.26°C (rough estimate)
[density ]

1.2251 (rough estimate)
[refractive index ]

1.4200 (estimate)
[Fp ]

100 °C
[storage temp. ]

0-6°C
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
[form ]

neat
[pka]

4.50±1.00(Predicted)
[CAS DataBase Reference]

5836-29-3(CAS DataBase Reference)
[NIST Chemistry Reference]

2H-1-benzopyran-2-one, 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-(5836-29-3)
[EPA Substance Registry System]

5836-29-3(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

T+
[Risk Statements ]

R27/28:Very Toxic in contact with skin and if swallowed .
R48/24/25:Toxic: danger of serious damage to health by prolonged exposure in contact with skin and if swallowed .
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
[Safety Statements ]

S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
[RIDADR ]

3027
[WGK Germany ]

3
[RTECS ]

GN7630000
[HazardClass ]

6.1(a)
[PackingGroup ]

II
[Hazardous Substances Data]

5836-29-3(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

4-Hydroxycoumarin-->1,2,3,4-Tetrahydro-1-naphthol
Hazard InformationBack Directory
[General Description]

Yellowish-white crystalline powder; colorless when pure; odorless. This material is used as a rodenticide, functioning as an anticoagulant that does not induce bait-shyness.
[Reactivity Profile]

Ketones, such as COUMATETRALYL, are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
[Health Hazard]

Overdosage with anticoagulants may cause acute bleeding. Pre-existing blood clotting disease or liver disease may be aggravated by exposure.
[Potential Exposure]

Coumatetralyl is used as a rodenticide, functioning as an anticoagulant that does not induce baitshyness.
[Fire Hazard]

(Non-Specific--Coumarin Derivative Pesticide, Solid, n.o.s.) This material may burn but does not ignite readily. Fire and runoff from fire control water may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Container may explode in heat of fire. Enolic form of compound has acidic properties and can form salts with metals.
[First aid]

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Speed in removing material from skin is of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Medical observation is recommended for 2436 hours following overexposure, as effects may be delayed.
[Shipping]

UN3027 Coumarin derivative pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
[Incompatibilities]

Contact with oxidizers may cause fire and explosion hazard. Keep away from metals.
[Description]

Coumatetralyl, is also called 4-hydroxy-3-(1,2,3,4- tetrahydro-1-naphthyl)coumarin, consists of colorless crystals which are slightly soluble in water (pH 7), benzene, toluene, diethyl ether, readily soluble in dimethylformamide, dichloromethane, isopropanol, soluble in alcohols, acetone.
Coumatetralyl is produced by the condensation of 4- hydroxycoumarin with 1,2,3,4-tetrahydro-1-naphthol (28). First introduced in 1956, coumatetralyl is one of the most widely used first-generation anticoagulants. It is not, however, available in the United States.
[Chemical Properties]

Coumatetralyl is a yellowish-white, crystalline solid.
[Waste Disposal]

Dissolve in a solvent and burn in a furnace by spraying in the solution
[Uses]

Coumatetralyl is used as an anticoagulant rodenticide. Coumatetralyl is widely used to control rodent populations.
[Definition]

ChEBI: Coumatetralyl is a hydroxycoumarin.
[Agricultural Uses]

Rodenticide: Coumatetralyl is used for rat control and functions as an anticoagulant, of the warfarin type, that does not induce bait-shyness. Not approved for use in EU countries or the U.S. There are 17 global suppliers.
[Trade name]

BAY® 25634; BAY ENE® 11183B; BAYER® 25,634; ENDOX®; ENDROCID®; ENDROCIDE®; RACUMIN®; RAUCUMIN® 57; RODENTIN®
[storage]

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area away from oxidizers
[Toxicity evaluation]

The acute toxicity for Norway rats is given as high but, as with many of these compounds, coumatetralyl is more potent when administered in consecutive daily doses. No satisfactory data are available on the acute oral toxicity of the compound to mice. However, a complete kill of mice was obtained in the laboratory following 21 days of feeding on coumatetralyl bait (29). Proprietary baits generally carry 0.375% coumatetralyl. Powder concentrates are available (strength 0.75%) which are used for the preparation of poisoned baits and as a tracking dust (18).
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-2H-1-benzopyran-2-one(5836-29-3).msds
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