| Identification | More | [Name]
2-AMINO-1-BUTANOL | [CAS]
5856-62-2 | [Synonyms]
(+/-)-2-AMINO-1-BUTANOL
2-AMINO-1-BUTANOL
D(+)-2-AMINO-1-BUTANOL
D-2-AMINO-1-BUTANOL
DL-2-AMINO-1-BUTANOL
LABOTEST-BB LT01409643
(S)-(+)-2-AMINO-1-BUTANOL
(S)(+)-2-AMINOBUTANOL
(S)-2-AMINOBUTANOL
(S)-(+)-2-AMINO-1-BUTANOL, 98+%
(S)-(+)-2-Amino-1-butanol, ca 95% ee, 98+%
1-Butanol, 2-amino-, (2S)-
L-2-Aminobutanol
(S)-(+)-2-Amino-1-butanol, 98+% ,ee:95%
(S)-(+)-2-Amino-1-butanol, ca 95% ee
(2S)-2-Amino-1-butanol
(S)-2-Amino-3-methyl-1-propanol | [EINECS(EC#)]
227-475-9 | [Molecular Formula]
C4H11NO | [MDL Number]
MFCD00008095 | [Molecular Weight]
89.14 | [MOL File]
5856-62-2.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to slightly yellowish viscous | [Melting point ]
-2 °C(lit.)
| [alpha ]
[α]D20 +9～+11° (neat) | [Boiling point ]
179-183 °C(lit.)
| [density ]
0.944 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.4521(lit.)
| [Fp ]
184 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
Soluble in water | [form ]
clear liquid | [pka]
pK1: 9.52(+1) (25°C) | [color ]
Clear colorless to slightly yellowish viscous liquid | [Optical Rotation]
[α]20/D +10°, neat | [Water Solubility ]
1000g/L at 25℃ | [Sensitive ]
Air Sensitive & Hygroscopic | [BRN ]
1718930 | [InChI]
1S/C4H11NO/c1-2-4(5)3-6/h4,6H,2-3,5H2,1H3/t4-/m0/s1 | [InChIKey]
JCBPETKZIGVZRE-BYPYZUCNSA-N | [SMILES]
CC[C@H](N)CO | [CAS DataBase Reference]
5856-62-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H314 | [Precautionary statements ]
P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns.
R37:Irritating to the respiratory system.
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2735 8/PG 3
| [WGK Germany ]
3
| [RTECS ]
EK9625000
| [REACH Registrations]
Inactive | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29221990 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Skin Corr. 1B |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to slightly yellowish viscous | [Uses]
(S)-(+)-2-Amino-1-butanol is a chiral amino alcohol that may be used in the synthesis of (S)-2-(6-benzylamino-9-isopropyl-9H-purin-2-ylamino) butan-1-ol, an (S)-enantiomer of roscovitine. It can also be used to synthesize homochiral 2-methylpyrroles. (S)-(+)-2-Amino-1-butanol is an intermediate for the synthesis of (S,S)-ethambutol, an antibacterial agent for treating tuberculosis. | [Synthesis]
To a 100 mL round-bottomed flask, aBH4 (0.2 g, 5 mmol) and THF (10 mL) were added. The suspension was stirred and the flask was immersed in an ice-water bath, and an ether solution of L-α-amino acids (1 mmol) and concentrated H2SO4 (0.132 mL) was added to | [Purification Methods]
They are purified by shaking with solid NaOH, filtering and distilling through a short column. The oxalate of the racemate has m 176o. They are strong bases and should be stored under N2 in the absence of CO2. The enantiomers have [] 20 ±12.5o (c 2, EtOH). [Johnson & Degering J Org Chem 8 7 1943, Nagao et al. J Org Chem 51 2392 1986, Santaniello et al. J Chem Soc, Perkin Trans 1 919 1985, Beilstein 4 H 291, 4 IV 1705.] |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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