| Identification | Back Directory | [Name]
Carlinoside | [CAS]
59952-97-5 | [Synonyms]
4H-1-Benzopyran-4-one, 8-α-L-arabinopyranosyl-2-(3,4-dihydroxyphenyl)-6-β-D-glucopyranosyl-5,7-dihydroxy- | [Molecular Formula]
C26H28O15 | [MDL Number]
MFCD02259465 | [MOL File]
59952-97-5.mol | [Molecular Weight]
580.49 |
| Hazard Information | Back Directory | [Uses]
Carlinoside is a flavone glycoside with hepatoprotective efficiency. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Carlinoside has the potential to intervene hyperbilirubinemia due to liver dysfunction[1]. | [Definition]
ChEBI: A C-glycosyl compound that is luteolin substituted at positions 8 and 6 by alpha-L-arabinopyranosyl and beta-D-glucosyl residues respectively. | [References]
[1] Kundu, et al. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Biochem Pharmacol. 2011 Nov 1;82(9):1186-97. DOI:10.1016/j.bcp.2011.07.069
[2] Das S, et al. Impact of edaphic factors and nutrient management on the hepatoprotective efficiency of Carlinoside purified from pigeon pea leaves: An evaluation of UGT1A1 activity in hepatitis induced organelles. Environ Res. 2018 Feb;161:512-523. DOI:10.1016/j.envres.2017.11.054 |
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