| Identification | Back Directory | [Name]
IODIPAMIDE | [CAS]
606-17-7 | [Synonyms]
adipiodon
bilignost
biligrafin
cholospect
transbilix
IODIPAMIDE
ADIPIODONE
cholografin
iodipamicacid
Iodipamide (200 mg)
LABOTEST-BB LT00772037
Adipic acid di(3-carboxy-2,4,6-triiodoanilide)
Adipic Acid Bis(3-carboxy-2,4,6-triiodoanilide)
3,3’-(adipoyldiimino)bis(2,4,6-triiodo-benzoicaci
3,3(ADIPOYLDIIMINO)BIS(2,4,6-TRIIODOBENZOIC ACID)
3,3'-ADIPOYLDIIMINOBIS(2,4,6-TRIIODOBENZOIC ACID)
2,2,4,4,6,6-hexaiodo-3,3-adipoyldiiminodi(benzoic acid)
3,3'-[(1,6-Dioxo-1,6-hexanediyl)diimino]bis[2,4,6-triiodobenzoic Acid
IodipaMide SynonyMs 3,3'(AdipoyldiiMino)-bis[2,4,6-triiodobenzoic acid]
3-[[6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid
3-[[6-(3-carboxy-2,4,6-triiodo-anilino)-6-keto-hexanoyl]amino]-2,4,6-triiodo-benzoic acid
3-[[6-[(3-carboxy-2,4,6-triiodo-phenyl)amino]-6-oxo-hexanoyl]amino]-2,4,6-triiodo-benzoic acid | [EINECS(EC#)]
210-105-5 | [Molecular Formula]
C20H14I6N2O6 | [MDL Number]
MFCD00058983 | [MOL File]
606-17-7.mol | [Molecular Weight]
1139.76 |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
306-308°C (dec.) | [Boiling point ]
908.6±65.0 °C(Predicted) | [density ]
2.5848 (estimate) | [refractive index ]
nD21.5 1.3294 (c = 0.445 in methanol) | [storage temp. ]
Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Very Slightly) | [form ]
neat | [pka]
pKa 3.5(H2O) (Uncertain) | [color ]
White | [Water Solubility ]
0.46g/L(20 ºC) | [Merck ]
5022 | [Major Application]
pharmaceutical (small molecule) | [InChIKey]
FFINMCNLQNTKLU-UHFFFAOYSA-N | [SMILES]
OC(=O)c1c(I)cc(I)c(NC(=O)CCCCC(=O)Nc2c(I)cc(I)c(C(O)=O)c2I)c1I | [EPA Substance Registry System]
Benzoic acid, 3,3'-[(1,6-dioxo-1,6-hexanediyl)diimino]bis[2,4,6-triiodo- (606-17-7) |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
antihypertensive, diuretic, activates K channels and AMPA receptors | [Uses]
Diagnostic aid (radiopaque medium-cholecystographic). | [Hazard]
Toxic by ingestion. | [Originator]
Cholografin,Squibb,US,1954 | [Definition]
ChEBI: Adipiodone is an organoiodine compound that is 3-amino-2,4,6-triiodobenzoic acid in which one of the amino hydrogens is substituted by a 6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl group. It is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography. It has a role as a radioopaque medium. It is an organoiodine compound, a member of benzoic acids and a secondary carboxamide. It is a conjugate acid of an adipiodone(2-). | [Manufacturing Process]
125 g of 2,4,6-triiodo-3-amino benzoic acid are dissolved in 250 cc of
chlorobenzene and 15 g of adipic acid dichloride are added at a temperature
between 110° and 130°C drop by drop to the solution. After evolution of
hydrochloric acid (about 2 to 3 hours) has ceased, the precipitated crude
adipic acid di-(3-carboxy-2,4,6-triiodo anilide) of the above formula is filtered
hot with suction, washed with chlorobenzene, extracted by boiling with
methanol and, for purification, dissolved in an amount of methanolic caustic
soda solution required for neutralization, filtered with charcoal, and
precipitated with dilute hydrochloric acid. Yield: 82.3 g, MP 306° to 308°C
(with decomposition). | [Brand name]
Pharmaceutic necessity for Iodipamide
Meglumine [Injection]. Cholografin (Bristol-Myers
Squibb). | [Therapeutic Function]
Diagnostic aid (radiopaque medium) | [storage]
Store at -20°C |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
|