| Identification | More | [Name]
2-Iodobenzoic acid | [CAS]
88-67-5 | [Synonyms]
2-IODOBENZOIC ACID
2-IODO BENZONIC ACID
BENZOIC ACID, 2-IODO-
IODOBENZOIC-2 ACID
'LGC' (4009)
O-IODOBENZOIC ACID
RARECHEM AL BO 0686
2-iodo-benzoicaci
Benzoic acid, o-iodo-
Kyselina o-jodbenzoova
kyselinao-jodbenzoova
o-iodo-benzoicaci
o-lodobenzoicacid
USAF ek-572
usafek-572
ACID O-IODOBENZOIC
o-Iodobenzoic Acid 2-Iodobenzoic acid
2-IODOBENZOIC ACID, SUBLIMED, 99+%
IodobenzoicAcid
2-Iodobenzoic acid, 98+% | [EINECS(EC#)]
201-850-7 | [Molecular Formula]
C7H5IO2 | [MDL Number]
MFCD00002419 | [Molecular Weight]
248.02 | [MOL File]
88-67-5.mol |
| Chemical Properties | Back Directory | [Appearance]
white crystal powder | [Melting point ]
160-162 °C(lit.)
| [Boiling point ]
313.9±25.0 °C(Predicted) | [density ]
2.25 | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Soluble in dimethyl sulfoxide and methanol | [form ]
Powder, Crystals or Flakes | [pka]
2.85(at 25℃) | [color ]
Light yellow to orange-brown | [Stability:]
Stable. Incompatible with strong oxidizing agents, strong bases. | [Water Solubility ]
sparingly soluble | [Sensitive ]
Light Sensitive | [Detection Methods]
HPLC,NMR,T | [Merck ]
14,5030 | [BRN ]
1861406 | [InChIKey]
CJNZAXGUTKBIHP-UHFFFAOYSA-N | [CAS DataBase Reference]
88-67-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzoic acid, 2-iodo-(88-67-5) | [Storage Precautions]
Store under nitrogen | [EPA Substance Registry System]
88-67-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection .
S24/25:Avoid contact with skin and eyes .
S22:Do not breathe dust .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
DH2975000
| [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
IRRITANT, LIGHT SENSITIVE | [HS Code ]
29163900 |
| Hazard Information | Back Directory | [Description]
2-iodobenzoic acid and its derivatives are important pharmaceutical and chemical raw materials, which are necessary for the synthesis of various high-iodine reagents. It is commonly used as a precursor for the synthesis of 2-Iodoxybenzoic acid (IBX) and Dess-Martin peridinane, which are used as mild oxidants. It is also used in Suziki reaction. | [Chemical Properties]
white crystal powder | [Uses]
suzuki reaction | [Definition]
ChEBI: An iodobenzoic acid with a single iodo substituent placed at the 2-position. | [Preparation]
2-Iodobenzoic acid is obtained from Anthranilic acid by diazotization and substitution. Diazotization of Anthranilic acid with sodium nitrite in the presence of sulfuric acid, control the temperature below 10℃, filter the diazotization solution, add the mixture of potassium iodide and sulfuric acid, stir for 10min after addition, and boil. Filter, wash with sodium thiosulfate solution, 2-Iodobenzoic acid can be recrystallized from water. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 93, p. 4841, 1971 DOI: 10.1021/ja00748a029 | [Purification Methods]
Crystallise the acid repeatedly from water and EtOH. Sublime it under vacuum at 100o. [Beilstein 9 IV 1030.] |
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