| Identification | More | [Name]
Myristicin | [CAS]
607-91-0 | [Synonyms]
4-METHOXY-6-[2-PROPENYL]-1,3-BENZODIOXOLE
5-ALLYL-2,3-(METHYLENDIOXY)ANISOLE
6-ALLYL-4-METHOXY-1,3-BENZODIOXOLE
MYRISTICIN
1,3-Benzodioxole, 4-methoxy-6-(2-propenyl)-
4-methoxy-6-(2-propenyl)-3-benzodioxole
5-allyl-1-methoxy-2,3-(methylenedioxy)-benzen
5-Allyl-1-methoxy-2,3-(methylenedioxy)benzene
Benzene, 5-allyl-1-methoxy-2,3-(methylenedioxy)-
Myristicine
myristicinfromparsleyleafoil
MYRISTICIN FROM PARSLEY OIL
MYRISTICIN(SG)
5-methoxysafrole
MYRISTICIN WITH GC
5-Allyl-2,3-(methylendioxy)anisole, 6-Allyl-4-methoxy-1,3-benzodioxole
4-Methoxy-6-allyl-1,3-benzodioxole
7-Methoxy-5-(2-propenyl)-1,3-benzodioxole | [EINECS(EC#)]
210-146-9 | [Molecular Formula]
C11H12O3 | [MDL Number]
MFCD00133549 | [Molecular Weight]
192.21 | [MOL File]
607-91-0.mol |
| Chemical Properties | Back Directory | [Definition]
The chief substance inthe ripe seeds of nutmeg (Myristica fragrans).It reduces the levels of cytochrome p-450 andinhibits monooxygenations catalyzed by thisenzyme. | [Appearance]
Crystalline phenolic ether with a strongodor. | [Melting point ]
-20℃ | [Boiling point ]
bp40 173° | [density ]
d2020 1.1437 | [refractive index ]
nD20 1.54032 | [storage temp. ]
2-8°C
| [solubility ]
Soluble in acetone, ethanol and methanol; | [form ]
oil
| [color ]
clear, light yellow
| [Odor]
at 100.00 %. spicy warm balsamic woody | [Odor Type]
spicy | [Water Solubility ]
insoluble in water | [BRN ]
166218 | [Stability:]
Light Sensitive | [Major Application]
food and beverages | [InChI]
1S/C11H12O3/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11/h3,5-6H,1,4,7H2,2H3 | [InChIKey]
BNWJOHGLIBDBOB-UHFFFAOYSA-N | [SMILES]
COc1cc(CC=C)cc2OCOc12 | [LogP]
2.586 (est) | [CAS DataBase Reference]
607-91-0(CAS DataBase Reference) | [NIST Chemistry Reference]
1,3-Benzodioxole, 4-methoxy-6-(2-propenyl)-(607-91-0) |
| Safety Data | Back Directory | [Symbol(GHS) ]
  
GHS07,GHS08,GHS09 | [Signal word ]
Warning | [Hazard statements ]
H302-H361f-H411 | [Precautionary statements ]
P202-P264-P270-P273-P301+P312-P308+P313 | [Risk Statements ]
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 3082 9/PG 3
| [WGK Germany ]
1
| [RTECS ]
CY2625000
| [F ]
10-23 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Aquatic Chronic 3
Repr. 2
STOT SE 3 | [Hazardous Substances Data]
607-91-0(Hazardous Substances Data) | [Toxicity]
A naturally occurring
methylenedioxyphenyl compound found in nutmeg. It has
been suggested that myristicin may be responsible, in whole or
in part, for the toxicity of nutmeg. The spice (5-15 g) causes
symptoms similar to atropine poisoning: flushing of the skin,
tachycardia, absence of salivation, and excitation of the CNS.
Euphoria and hallucinations have given rise to abuse of this
material. As a methylenedioxyphenyl compound, myristicin
gives rise to a type III spectrum with reduced cytochrome
P450 and can inhibit monooxygenations catalyzed by this cytochrome. |
| Hazard Information | Back Directory | [Hazard]
Poison; moderately toxic; mutagen. | [Description]
Myristicin is an alkenylbenzene present in small amounts in the essential oil of nutmeg that is reported to act as a serotonin receptor antagonist, a weak monamine oxidase inhibitor, and to produce hallucinogenic effects.1 Abuse of myristicin has led to fatal poisoning, which has prompted improved methods for HPLC determination of myristicin in human plasma.2 This product is intended for forensic and research purposes. | [Chemical Properties]
Crystalline phenolic ether with a strongodor. | [Uses]
A naturally occurring insecticide and acaricide with possible neurotoxic effects on neuroblastoma cells | [References]
[1] KALBHEN Priv Doz Dr D A. Nutmeg as a Narcotic. A Contribution to the Chemistry and Pharmacology of Nutmeg (Myristica fragrans)[J]. Angewandte Chemie International Edition, 1971, 10 6: 370-374. DOI: 10.1002/anie.197103701
[2] ANDRZEJ L DAWIDOWICZ Michal P D. Simple and rapid determination of myristicin in human serum.[J]. Forensic Toxicology, 2013, 31 1: 119-123. DOI: 10.1007/s11419-012-0151-8 |
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J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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