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61077-78-9

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61077-78-9 Structure

61077-78-9 Structure

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[Name] Tanshinone IIA anhydride
[CAS] 61077-78-9
[Synonyms] Tanshinone IIA anhydride
[Molecular Formula] C19H18O4
[MOL File] 61077-78-9.mol
[Molecular Weight] 310.344

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[form ] Solid
[color ] Light yellow to yellow

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[Uses] Tanshinone IIA anhydride is a potent and irreversible human carboxylesterase (CE) inhibitor with Ki values of 1.9 nM and 1.4 nM for human CE1 and the human intestinal CE (hiCE), respectively[1].
[References] [1] M Jason Hatfield, et al. Potent, Irreversible Inhibition of Human Carboxylesterases by Tanshinone Anhydrides Isolated from Salvia miltiorrhiza ("Danshen"). J Nat Prod. 2018 Nov 26;81(11):2410-2418. DOI:10.1021/acs.jnatprod.8b00378

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