| Identification | Back Directory | [Name]
DeMethoxycapillarisin | [CAS]
61854-36-2 | [Synonyms]
DeMethoxycapillarisin
5,7-dihydroxy-2-(4-hydroxyphenoxy)chromen-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenoxy)- | [Molecular Formula]
C15H10O6 | [MDL Number]
MFCD06410654 | [MOL File]
61854-36-2.mol | [Molecular Weight]
286.24 |
| Chemical Properties | Back Directory | [Melting point ]
>280 °C (decomp) | [Boiling point ]
535.9±50.0 °C(Predicted) | [density ]
1.591±0.06 g/cm3(Predicted) | [pka]
6.39±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Demethoxycapillarisin (6-Demethoxycapillarisin) inhibits PEPCK mRNA levels (IC50: 43 μM) by activation of the PI3K pathway. Demethoxycapillarisin decreases glucose production[1]. | [Definition]
ChEBI: 6-Demethoxycapillarisin is a member of coumarins. | [References]
[1] Govorko D, et al. Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line. Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1503-10. DOI:10.1152/ajpendo.00420.2007 |
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