| Identification | More | [Name]
2,4-Dihydroxypyridine | [CAS]
626-03-9 | [Synonyms]
2(1H)-PYRIDINONE, 4-HYDROXY-
2,4-DIHYDROXYPYRIDINE
2,4-PYRIDINEDIOL
3-DEAZAURACIL
4-HYDROXY-2-PYRIDONE
PYRIDINE-2,4-DIOL
TIMTEC-BB SBB004331
4-hydroxy-2(1h)-pyridinon
4-hydroxy-2(1h)-pyridon
2,4-Dihydroxypyridine,97%
3-Deazauracil, 4-Hydroxy-2-pyridone, 2,4-PYridinediol
2(1H)-Pyridone, 4-hydroxy.
2,4-Dihydroxypyridine, HPLC 97%
2,4-Dihydroxypyridine
NSC 119859
NSC 37839
2,4-Pyridinediol, 3-Deazauracil, 4-Hydroxy-2-pyridone
2-Hydroxy-1H-pyridin-4-one
4-Hydroxy-2(1H)-pyridinone
2,4-Dihydroxypyridine ,98% | [EINECS(EC#)]
210-924-8 | [Molecular Formula]
C5H5NO2 | [MDL Number]
MFCD00006273 | [Molecular Weight]
111.1 | [MOL File]
626-03-9.mol |
| Chemical Properties | Back Directory | [Appearance]
white to yellow-beige crystals or cryst. powder | [Melting point ]
272-276 °C (lit.) | [Boiling point ]
208.19°C (rough estimate) | [density ]
1.3113 (rough estimate) | [refractive index ]
1.4260 (estimate) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO, Methanol | [form ]
powder
| [pka]
pK1:1.37(+1);pK2:6.45(0);pK3:13(+1) (20°C) | [color ]
light yellow
| [Water Solubility ]
6.211g/L(20 ºC) | [Detection Methods]
HPLC,NMR | [BRN ]
108533 | [InChI]
InChI=1S/C5H5NO2/c7-4-1-2-6-5(8)3-4/h1-3H,(H2,6,7,8) | [InChIKey]
ZEZJPIDPVXJEME-UHFFFAOYSA-N | [SMILES]
C1(=O)NC=CC(O)=C1 | [CAS DataBase Reference]
626-03-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
UV1146800
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Application]
2,4-Dihydroxypyridine is profusely employed in multiple fields such as pesticide design, pharmacology, and clinical therapeutics[1]. This compound could used as a new growth-directing agent to to prepare AgPt nanorings supported on reduced graphene oxide (AgPt NRs-rGO) through a facile one-pot wet-chemical route. This label-free electrochemical immunosensor could be used for the sensitive detection of CEA[2].
| [Description]
2,4-Dihydroxypyridine belongs to the class of organic compounds known as pyridinones. Pyridinones are compounds containing a pyridine ring, which bears a ketone. This compound has been identified in human blood. 2,4-dihydroxypyridine is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically 2,4-Dihydroxypyridine is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources.
| [Chemical Properties]
white to yellow-beige crystals or cryst. powder | [Uses]
2,4-Dihydroxypyridine (3-deazauracil) was used in the synthesis of diazaphenoxathiin skeleton. | [Definition]
ChEBI: 2,4-Dihydroxypyridine is a pyridone. | [General Description]
2,4-Dihydroxypyridine (3-deazauracil) is a potent inhibitor of dihydrouracil dehydrogenase. | [References]
[1] Pajares A, et al. Ionization effects on the sensitized photooxidation of 2,3-dihydroxypyridine and 2,4-dihydroxypyridine: a kinetic study. Journal of Photochemistry and Photobiology A: Chemistry, 2002; 153: 101-107.
[2] Wang R, et al. A label-free electrochemical immunosensor based on AgPt nanorings supported on reduced graphene oxide for ultrasensitive analysis of tumor marker. Sensors and Actuators B: Chemical, 2017; 254: 1174-1181. |
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