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628-68-2

628-68-2 Structure

628-68-2 Structure
IdentificationMore
[Name]

Diethyleneglycol diacetate
[CAS]

628-68-2
[Synonyms]

2,2'-OXYBISETHANOL DIACETATE
BIS (2-ACETOXYETHYL) ETHER
DIETHYLENE GLYCOL DIACETATE
OXYBIS(2-ETHYL ACETATE)
OXYDIETHYLENE ACETATE
2,2’-oxybis-ethanodiacetate
2-[2-(Acetyloxy)ethoxy]ethyl acetate
aceticacid,oxydiethyleneester
aceticacid2-(2-acetoxy-ethoxy)-ethylester
Diglycol, diacetate
Ethanol,2,2’-oxybis-,diacetate
oxydiethylenedi(acetate)
2-acetoxyethyl ether
digol diacetate
Diethylene glycol diacetate: (Diacetate-1,1-oxybis-ethanol)
2,2μ-Oxybisethanol diacetate, Bis(2-acetoxyethyl) ether, Oxydiethylene acetate
1,1'-Oxybis(2-acetoxyethane)
2,2'-Oxybis(ethanol acetate)
Diacetic acid oxybisethylene ester
[EINECS(EC#)]

211-049-4
[Molecular Formula]

C8H14O5
[MDL Number]

MFCD00026211
[Molecular Weight]

190.19
[MOL File]

628-68-2.mol
Chemical PropertiesBack Directory
[Melting point ]

19°C
[Boiling point ]

200°C (estimate)
[density ]

1.101 g/mL at 25 °C
[refractive index ]

n20/D 1.431
[Fp ]

>230 °F
[form ]

powder to lump to clear liquid
[color ]

White or Colorless to Almost white or Almost colorless
[InChI]

1S/C8H14O5/c1-7(9)12-5-3-11-4-6-13-8(2)10/h3-6H2,1-2H3
[InChIKey]

UBPGILLNMDGSDS-UHFFFAOYSA-N
[SMILES]

CC(=O)OCCOCCOC(C)=O
[LogP]

0.13 at 25℃
[CAS DataBase Reference]

628-68-2(CAS DataBase Reference)
[NIST Chemistry Reference]

Ethanol, 2,2'-oxybis-, diacetate(628-68-2)
[EPA Substance Registry System]

628-68-2(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H319
[Precautionary statements ]

P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

R36:Irritating to the eyes.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

3
[RTECS ]

AJ1800000
[TSCA ]

TSCA listed
[REACH Registrations]

Active
[HS Code ]

29153900
[Storage Class]

10 - Combustible liquids
[Hazard Classifications]

Eye Irrit. 2
Hazard InformationBack Directory
[Uses]

Diethylene glycol diacetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Definition]

ChEBI: An acetate ester that is the diacetate obtained by the formal condensation of the two hydroxy groups of diethylene glycol with two molecules of acetic acid respectively.
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Spectrum DetailBack Directory
[Spectrum Detail]

Diethyleneglycol diacetate(628-68-2)MS
Diethyleneglycol diacetate(628-68-2)1HNMR
Diethyleneglycol diacetate(628-68-2)13CNMR
Diethyleneglycol diacetate(628-68-2)IR1
Diethyleneglycol diacetate(628-68-2)IR2
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

628-68-2(sigmaaldrich)
[TCI AMERICA]

Diethylene Glycol Diacetate,>98.0%(GC)(628-68-2)
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