Identification | More | [Name]
1-(2-Aminoethyl)imidazolidin-2-one | [CAS]
6281-42-1 | [Synonyms]
1-(2-AMINOETHYL)-2-IMIDAZOLIDINONE 1-(2-AMINOETHYL)-2-IMIDAZOLIDONE 1-(2-AMINOETHYL)IMIDAZOLIDIN-2-ONE 1-(BETA-AMINOETHYL)-2-IMIDAZOLIDONE BUTTPARK 52\06-90 CHEMBRDG-BB 4005390 1-(2-aminoethyl)-2-imidazolidinon 1-(2-aminoethyl)-2-imidazolone 2-Imidazolidinone, 1-(2-aminoethyl)- 1-(2-aminoethyl)imidazolidin-2-one(50% solution in i.p.a.) 1-(2-Aminoethyl)-imidazolidinone 1-(2-aminoethyl)imidazolidin-2-one(50% solution in Isopropyl alcohol) 1-(2-Aminoethyl)imidazolidin-2-one ,96% | [EINECS(EC#)]
228-491-9 | [Molecular Formula]
C5H11N3O | [MDL Number]
MFCD00086348 | [Molecular Weight]
129.16 | [MOL File]
6281-42-1.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S22:Do not breathe dust . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
3259 | [Hazard Note ]
Irritant | [HS Code ]
29332900 |
Hazard Information | Back Directory | [Chemical Properties]
Colorless to off-white liquid | [Uses]
1-(2-Aminoethyl)-2-imidazolidone is a useful research chemical compound used in the preparation of alkyl and aryl azides by chemoselective diazotization of primary amines with in situ-generated fluorosulfonyl azide and their use in the preparation of a combinatorial library of 1,2,3-triazole. | [Flammability and Explosibility]
Notclassified | [Synthesis]
693 kg (6.728 kmol) of diethylenetriamine (DETA) was added to a 1 m3 stirred reactor equipped with a double jacket, a liquid feed device, a nitrogen inerting system, a reaction vessel, and a scrubber tower for recovery of ammonia and ammonia solution. The reaction system was warmed up to 130°C while nitrogen was introduced to remove oxygen from the DETA. When the temperature reached 130 °C, slow addition of a 40% aqueous urea solution totaling 671.4 kg (4.476 kmol) was initiated, resulting in a molar ratio of DETA to urea of 1.5:1. The addition of the urea solution continued for a period of 4 h in batches. The ammonia released immediately at the beginning of the reaction was recovered through a scrubbing tower, and the scrubbing solution and the aqueous ammonia solution were collected in a special container. After the addition was completed, the reaction mixture was kept at 130°C for 1.5 hours to ensure complete water removal. Subsequently, the reaction temperature was gradually increased: first to 140 °C in 45 min and held for 45 min, then to 150 °C and held for 45 min, and finally at 160 °C for 5 h. The reaction temperature was then increased to 140 °C in 45 min and held for 45 min. At the end of the reaction, the system was cooled to 125 °C and the excess DETA was removed by distillation under a reduced pressure of 10 to 1.5 mbar and a mild nitrogen stream, a process that did not take more than 5 hours. After restoring the system to atmospheric pressure, it was cooled to 60 °C and the product was removed from the reactor. The resulting product contained 95-96% of 1-(2-aminoethyl)-2-imidazolidinone (UDETA) and 1-2.5% of tetraethyleneurea (TETU). | [References]
[1] Patent: US2013/23667, 2013, A1. Location in patent: Paragraph 0044; 0045; 0046; 0047 [2] Patent: US2613212, 1950, [3] Patent: US6630599, 2003, B1. Location in patent: Page/Page column 10 |
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