ChemicalBook--->CAS DataBase List--->6281-58-9

6281-58-9

6281-58-9 Structure

6281-58-9 Structure
IdentificationBack Directory
[Name]

4-(2-methyl-1-pyrrolidyl)-7-chloroquinoline
[CAS]

6281-58-9
[Synonyms]

NX-357
Plaquenil Impurity 2
Chloroquine Impurity A
Hydroxychloroquine Impurity F
Hydroxychloroquine sulfate Impurity F
Hydroxychloroquine Sulphate Imp.1 HCl
Hydroxychloroquine Sulfate EP Impurity F
4-(2-methyl-1-pyrrolidyl)-7-chloroquinoline
7-Chloro-4-(2-methyl-1-pyrrolidinyl)quinoline
7-Chloro-4-(2-methylpyrrolidin-1-yl)quinoline
4-(2-Methyl-1-pyrrolidinyl)-7-chloroquinoline
Quinoline, 7-chloro-4-(2-methyl-1-pyrrolidinyl)-
Hydroxychloroquine Sulfate Impurity 2(Hydroxychloroquine Sulfate EP Impurity F)
[Molecular Formula]

C14H15ClN2
[MDL Number]

MFCD01685619
[MOL File]

6281-58-9.mol
[Molecular Weight]

246.74
Chemical PropertiesBack Directory
[Boiling point ]

141-147 °C(Press: 0.02 Torr)
[density ]

1.214±0.06 g/cm3(Predicted)
[storage temp. ]

Refrigerator
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Oil
[pka]

7.70±0.50(Predicted)
[color ]

Yellow to Light Brown
[InChI]

InChI=1S/C14H15ClN2/c1-10-3-2-8-17(10)14-6-7-16-13-9-11(15)4-5-12(13)14/h4-7,9-10H,2-3,8H2,1H3
[InChIKey]

GYORBDCAYLXAIL-UHFFFAOYSA-N
[SMILES]

N1C2C(=CC=C(Cl)C=2)C(N2CCCC2C)=CC=1
Hazard InformationBack Directory
[Uses]

7-Chloro-4-(2-methyl-1-pyrrolidinyl)-quinoline is a Chloroquine (C380315), iimpurity. Chloroquine is used in the treatment of malaria and MDR-strains.
Safety DataBack Directory
[Toxicity]

LD50 intravenous in mouse: 56mg/kg
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