Identification | Back Directory | [Name]
MRS 2500 tetraammonium salt | [CAS]
630103-23-0 | [Synonyms]
MRS2500 tetraammonium MRS-2500 tetraammonium,MRS2500 tetraammonium | [Molecular Formula]
C13H21IN6O8P2 | [MOL File]
630103-23-0.mol | [Molecular Weight]
578.2 |
Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Powder | [color ]
White to off-white | [Water Solubility ]
Soluble to 100 mM in water |
Hazard Information | Back Directory | [Uses]
MRS 2500 tetraammonium salt is a highly potent and selective antagonist of the platelet P2Y1 receptor. It inhibits ADP-induced aggregation of human platelets. | [in vivo]
MRS2500 (2 mg/kg; i.v.) decreases acute systemic thromboembolism through selective inhibition of the P2Y1 receptor[3]. ?
MRS2500 exhibited strong antithrombotic efficacy in the prevention of arterial thrombosis in the monkey ECAT model[4].. Animal Model: | 20-25 g WT Male mice (acute vascular occlusion model)[3] | Dosage: | 2 mg/kg | Administration: | Intravenous | Result: | Reduced platelet consumption.
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| [storage]
Store at -20°C |
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BOC Sciences
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https://www.bocsci.com |
Company Name: |
R&D Systems, Inc
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18003437475 18003437475 |
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www.rndsystems.com |
Company Name: |
Carbosynth
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+86 512 6260 5585 |
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www.carbosynth.com |
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