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630103-23-0

630103-23-0 Structure

630103-23-0 Structure
IdentificationBack Directory
[Name]

MRS 2500 tetraammonium salt
[CAS]

630103-23-0
[Synonyms]

MRS2500 tetraammonium
MRS-2500 tetraammonium,MRS2500 tetraammonium
[Molecular Formula]

C13H21IN6O8P2
[MOL File]

630103-23-0.mol
[Molecular Weight]

578.2
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Powder
[color ]

White to off-white
[Water Solubility ]

Soluble to 100 mM in water
Hazard InformationBack Directory
[Uses]

MRS 2500 tetraammonium salt is a highly potent and selective antagonist of the platelet P2Y1 receptor. It inhibits ADP-induced aggregation of human platelets.
[in vivo]

MRS2500 (2 mg/kg; i.v.) decreases acute systemic thromboembolism through selective inhibition of the P2Y1 receptor[3].
? MRS2500 exhibited strong antithrombotic efficacy in the prevention of arterial thrombosis in the monkey ECAT model[4]..

Animal Model:20-25 g WT Male mice (acute vascular occlusion model)[3]
Dosage:2 mg/kg
Administration:Intravenous
Result:Reduced platelet consumption.
[storage]

Store at -20°C
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