| Identification | Back Directory | [Name]
Malabaricone B | [CAS]
63335-24-0 | [Synonyms]
Malabaricone B
1-(2,6-Dihydroxyphenyl)-9-(4-hydroxyphenyl)-1-nonanone
1-Nonanone, 1-(2,6-dihydroxyphenyl)-9-(4-hydroxyphenyl)- | [Molecular Formula]
C21H26O4 | [MDL Number]
MFCD31557591 | [MOL File]
63335-24-0.mol | [Molecular Weight]
342.43 |
| Chemical Properties | Back Directory | [Melting point ]
100-102 °C | [Boiling point ]
536.4±45.0 °C(Predicted) | [density ]
1.170±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml | [form ]
A crystalline solid | [pka]
7.48±0.35(Predicted) | [color ]
Off-white to light yellow | [InChI]
InChI=1S/C21H26O4/c22-17-14-12-16(13-15-17)8-5-3-1-2-4-6-9-18(23)21-19(24)10-7-11-20(21)25/h7,10-15,22,24-25H,1-6,8-9H2 | [InChIKey]
KOAPDMKKECXPHX-UHFFFAOYSA-N | [SMILES]
C(C1=C(O)C=CC=C1O)(=O)CCCCCCCCC1=CC=C(O)C=C1 |
| Hazard Information | Back Directory | [Uses]
Malabaricone B is a diarylnonanoid isolated from the Myristicaceae family of plants, and it is found to induce mitochondrial damage in human and mouse lung cancer cells via p53-independent pathway. | [in vivo]
Malabaricone B (100 mg/kg; p.o; alternate day, 23 days) inhibits lung tumor (xenograft) growth in SCID mice[1]. |
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