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637-01-4

637-01-4 Structure

637-01-4 Structure
IdentificationMore
[Name]

N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
[CAS]

637-01-4
[Synonyms]

N,N,N',N'-TETRAMETHYL-1,4-BENZENEDIAMINE, DIHYDROCHLORIDE
N,N,N',N'-TETRAMETHYL-1,4-PHENYLENEDIAMINE DIHYDROCHLORIDE
N,N,N',N'-TETRAMETHYL-1,4-PHENYLENEDIAMMONIUM DICHLORIDE
N,N,N',N'-TETRAMETHYL-4-PHENYLENEDIAMINE DIHYDROCHLORIDE
N,N,N',N'-TETRAMETHYL-P-PHENYLENEDIAMINE 2HCL
N,N,N',N'-TETRAMETHYL-P-PHENYLENEDIAMINE DI HCL
N,N,N',N'-TETRAMETHYL-P-PHENYLENEDIAMINE DIHYDROCHLORIDE
TMPD
TMPD DIHYDROCHLORIDE
WURSTER-REAGENT
WURSTER'S REAGENT
WURSTER'S REAGENT DIHYDROCHLORIDE
1,4-Benzenediamine,N,N,N’,N’-tetramethyl-,dihydrochloride
4-benzenediamine,n,n,n’,n’-tetramethyl-dihydrochloride
n,n,ni,ni-tetramethyl-p-phenylenediaminedihydrochloride
p-phenylenediamine,n,n,n’,n’,tetramethyl-,dihydrochloride
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
NNN'N'-Tetramethyl-p-phenylene-diamine dihydrochloride
N,N,N',N'-Tetramethyl-p-phenylenediammonium dichloride
N,N,N',N'-TETRAMETHYL-P-*PHENYLENEDIAMIN E DIHYDROCH
N,NnTetramethyl-P-Phenylenediamine
[EINECS(EC#)]

211-274-8
[Molecular Formula]

C10H18Cl2N2
[MDL Number]

MFCD00012482
[Molecular Weight]

237.17
[MOL File]

637-01-4.mol
Chemical PropertiesBack Directory
[Appearance]

Off white to gray powder
[Melting point ]

222-224 °C(lit.)
[Boiling point ]

378.54°C (rough estimate)
[density ]

1.1961 (rough estimate)
[refractive index ]

1.6400 (estimate)
[storage temp. ]

Store at RT.
[solubility ]

H2O: soluble500mg/10 mL
[form ]

powder
[color ]

off-white to gray
[Stability:]

Stable. Incompatible with strong oxidizing agents, strong bases.
[Water Solubility ]

SOLUBLE
[Sensitive ]

Light Sensitive
[BRN ]

5132096
[Major Application]

diagnostic assay manufacturing
hematology
histology
[InChI]

InChI=1S/C10H16N2.ClH/c1-11(2)9-5-7-10(8-6-9)12(3)4;/h5-8H,1-4H3;1H
[InChIKey]

DNRUPOAHVJBDJE-UHFFFAOYSA-N
[SMILES]

N(C1C=CC(N(C)C)=CC=1)(C)C.Cl
[CAS DataBase Reference]

637-01-4(CAS DataBase Reference)
[EPA Substance Registry System]

637-01-4(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
[Hazard Codes ]

Xi,Xn
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R40:Limited evidence of a carcinogenic effect.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S36/37:Wear suitable protective clothing and gloves .
S22:Do not breathe dust .
[RIDADR ]

2811
[WGK Germany ]

3
[F ]

8
[TSCA ]

Yes
[HazardClass ]

6.1(a)
[PackingGroup ]

II
[HS Code ]

29215190
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Methanol-->Sulfuric acid-->Sodium chloride-->Acetone-->Calcium chloride-->Copper(I) chloride-->Sodium bromide-->p-Phenylenediamine dihydrochloride
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride(637-01-4).msds
Hazard InformationBack Directory
[Chemical Properties]

Off white to gray powder
[Uses]

N,N,N′,N′-Tetramethyl-p-phenylenediamine dihydrochloride has been used to determine the oxidase activity displayed by various microorganisms.
[Uses]

An oxidizable compound
[Uses]

N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. It is also used as a test reagent in microbiology for the classification of cytochrome oxidase positive aerobic microorganisms. It finds application as a detection of peroxidases on polyacrylamide gels.
[General Description]

N,N,N′,N′-Tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is a redox mediator used in the oxidase test for detecting bacterial cytochrome c oxidases. TMPD is commonly used to perform the oxidase test for the colorimetric identification of pathogenic and non-pathogenic bacteria.
[Purification Methods]

Crystallise the salt from isopropyl or n-butyl alcohols, saturated with HCl. Treat it with aqueous NaOH to give the free base (see previous entry) which is filtered, dried and sublimed in a vacuum. [Guarr et al. J Am Chem Soc 107 5104 1985, Beilstein 13 H 74.]
Spectrum DetailBack Directory
[Spectrum Detail]

N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride(637-01-4)MS
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride(637-01-4)1HNMR
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride(637-01-4)IR1
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride(637-01-4)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

N,N,N',N'-Tetramethyl-p-phenylenediaminedihydrochloride,99%(637-01-4)
[Alfa Aesar]

N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%(637-01-4)
[Sigma Aldrich]

637-01-4(sigmaaldrich)
[TCI AMERICA]

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Dihydrochloride,>98.0%(T)(637-01-4)
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