| Identification | More | [Name]
FLUOROACETAMIDE | [CAS]
640-19-7 | [Synonyms]
2-FLUOROACETAMIDE
2-FLUOROACETIC AMIDE
ALPHA-FLUOROACETAMIDE
BARON(R)
COMPOUND 1081(R)
FLUORACETAMIDE
FLUORAKIL
Fluorakil 100
FLUORAKIL 100(R)
FLUOROACETAMIDE
FUSSOL(R)
NAVRON
NAVRON(R)
RHODEX
RODEX
RODEX(R)
YANOCK
YANOCK(R)
1081
2-fluoro-acetamid | [EINECS(EC#)]
211-363-1 | [Molecular Formula]
C2H4FNO | [MDL Number]
MFCD00008026 | [Molecular Weight]
77.06 | [MOL File]
640-19-7.mol |
| Chemical Properties | Back Directory | [Description]
Fluoroacetamide is an odourless, tasteless, white, crystalline water soluble. It is a fluorinated
amide and reacts with azo and diazo compounds to generate toxic gases. Flammable
gases are formed by the reaction of organic amides/imides with strong reducing agents.
Fluoroacetamide is used as a rodenticide and insecticide to control rabbits but is dangerous
for other species of pests, farm livestock, and humans. Fluoroacetamide is a noncombustible
substance itself and does not burn but may decompose upon heating to
produce irritating, corrosive, and/or toxic fumes. On decomposition, fluoroacetamide
releases nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon
dioxide, HF gas, and nitrogen gas. | [Appearance]
Fluoroacetamide is a colorless, crystalline
solid. | [Melting point ]
106-108 °C(lit.) | [Boiling point ]
259.0±10.0 °C(Predicted) | [density ]
1.1170 (estimate) | [solubility ]
DMSO (Soluble), Methanol (Slightly) | [form ]
Solid | [pka]
14.60±0.40(Predicted) | [color ]
Off-White to Pale Beige | [Stability:]
Stable. | [Merck ]
13,4193 | [BRN ]
1739054 | [CAS DataBase Reference]
640-19-7(CAS DataBase Reference) | [EPA Substance Registry System]
Fluoroacetamide (640-19-7) |
| Safety Data | Back Directory | [Hazard Codes ]
T+,T,Xi | [Risk Statements ]
R24:Toxic in contact with skin.
R28:Very Toxic if swallowed. | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2811 6.1/PG 2
| [WGK Germany ]
2
| [RTECS ]
AC1225000
| [Hazard Note ]
Highly Toxic/Irritant | [HazardClass ]
6.1(a) | [PackingGroup ]
I | [HS Code ]
29241200 | [Safety Profile]
A human poison by an
unspecified route. Poison experimentally by
ingestion, skin contact, intraperitoneal,
subcutaneous, and intravenous routes.
Human systemic effects by unspecified
route: convulsions, coma, nausea and
vomiting. Experimental reproductive effects.
Mutation data reported. Used as an
insecticide and rodenticide. When heated to
decomposition it emits very toxic fumes of
Fand NOx. See also FLUORIDES. | [Hazardous Substances Data]
640-19-7(Hazardous Substances Data) | [Toxicity]
LD50 i.p. in mice: 85 mg/kg (Matsumura, O'Brien) |
| Hazard Information | Back Directory | [General Description]
Colorless crystalline powder. Used as a rodenticide. Highly toxic. | [Reactivity Profile]
FLUOROACETAMIDE(640-19-7) is a fluorinated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). | [Air & Water Reactions]
Very soluble in water [Farm Chemicals] | [Hazard]
Extremely toxic; poison; mutagen. | [Health Hazard]
This material is super toxic; probable oral lethal dose in humans is less than 5 mg/kg, or a taste (less than 7 drops) for a 150-lb. person. Chemically inhibits oxygen metabolism by cells with critical damage occurring to the heart, brain, and lungs resulting in heart failure, respiratory arrest, convulsions, and death. | [Potential Exposure]
This material is an organofluorine
rodenticide; insecticide proposed mainly for use on fruits to
combat scale insects, aphids, and mites. Use is largely
restricted to licensed pest control operators. | [Fire Hazard]
Emits very toxic fumes of fluorine containing compounds and nitrogen oxides when heated to decomposition. Avoid decomposing heat. | [First aid]
Acute exposure to fluoroacetamide may require
decontamination and life support for the victim. Inhalation:
Move victim to fresh air. Call 911 or emergency medical
service. Evaluate vital signs. If no pulse is detected, pro vide CPR. If possible, rush victim to a healthcare facility.
Give artificial respiration if victim is not breathing. Do not
use mouth-to-mouth method if victim ingested or inhaled
the substance; give artificial respiration with the aid of a
pocket mask equipped with a one-way valve or other
proper respiratory medical device. Administer oxygen if
breathing is difficult. Eye Exposure: Remove any contact
lenses at once and flush eyes with lukewarm water for
15 minutes. Skin Exposure: Follow steps under inhalation
above. Wash exposed skin areas three times with soap and
water. Rush to healthcare facility. Ingestion: Evaluate vital
signs, including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. Obtain authori zation and/or further instructions from the local hospital for
performance of other invasive procedures. Remove and isolate
contaminated clothing and shoes. In case of contact with sub stance, immediately flush skin or eyes with running water for
at least 20 minutes. For minor skin contact, avoid spreading
material on unaffected skin. Keep victim warm and quiet.
Effects of exposure (inhalation, ingestion or skin contact) to
substance may be delayed. Ensure that medical personnel are
aware of the material(s) involved and take precautions to
protect themselves. Medical observation is recommended for
24 to 48 hours after breathing overexposure, as pulmonary
edema may be delayed. As first aid for pulmonary edema, a
doctor or authorized paramedic may consider administering a
drug or other inhalation therapy. | [Shipping]
UN2811 Toxic solids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required. | [Incompatibilities]
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explo sions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. | [Chemical Properties]
crystals | [Chemical Properties]
Fluoroacetamide is a colorless, crystalline
solid. | [Waste Disposal]
Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant
(≥100 kg/mo) must conform with EPA regulations govern ing storage, transportation, treatment, and waste disposal. | [Uses]
Rodenticide. Insecticide proposed mainly for use on fruits to combat scale insects, aphids, and mites. | [Definition]
ChEBI: Acetamide substituted at C-2 by a fluorine atom. | [Production Methods]
Fluoroacetamide is produced by reaction of α-chloroacetamide
with potassium fluoride in tetrachloroethylene
at elevated temperature. | [storage]
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area. | [Purification Methods]
Crystallise fluoroacetamide from chloroform and dry it in a vacuum. [Beilstein 2 IV 454.] |
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