| Identification | More | [Name]
Nicotine ditartrate | [CAS]
65-31-6 | [Synonyms]
(-)-1-METHYL-2-[3-PYRIDYL]PYRROLIDINE DI-(+) TARTRATE SALT
NICOTINE BI-L-(+)-TARTRATE
NICOTINE BITARTRATE
(-)-NICOTINE, DITARTRATE
NICOTINE HYDROGEN-L-TARTRATE
(-)-NICOTINE HYDROGEN TARTRATE SALT
NICOTINE TARTRATE
(-)-NICOTINE TARTRATE SALT
(S)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINE, DI-D-TARTRATE
(S)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINE TARTRATE SALT
(S)-3-(1-METHYL-2-PYRROLINDINYL)PYRIDINE, DI-D-TARTRATE
(S)-3-(1-METHYL-2-PYRROLINDINYL)PYRIDINE TARTRATE SALT
(-)-nicotinehydrogentartrate
nicotine,tartrate(1:2)
nicotineacidtartrate
nicotinehydrogentartrate
nikotinbitartrat
pyridine,3-(1-methyl-2-pyrrolidinyl)-,(s)-,(r-(r*,r*))-2,3-dihydroxybutane
pyridine,3-(1-methyl-2-pyrrolidinyl)-,(s)-,(r-(r*,r*))-2,3-dihydroxybutanedi
tartratedenicotine | [EINECS(EC#)]
200-607-2 | [Molecular Formula]
C18H26N2O12 | [MDL Number]
MFCD00069368 | [Molecular Weight]
462.41 | [MOL File]
65-31-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
90° | [alpha ]
D20 +26° (c = 10) | [storage temp. ]
Desiccate at RT | [solubility ]
H2O: 50 mg/mL
| [form ]
powder
| [color ]
white to off-white
| [Optical Rotation]
[α]/D +20 to +26°, c = 1.0 in water | [InChI]
1S/C10H14N2.2C4H6O6/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;2*5-1(3(7)8)2(6)4(9)10/h2,4,6,8,10H,3,5,7H2,1H3;2*1-2,5-6H,(H,7,8)(H,9,10)/t;2*1-,2-/m.11/s1 | [InChIKey]
RFEJUZJILGIRHQ-UHFFFAOYSA-N | [SMILES]
N1(C(CCC1)c2cnccc2)C.O[C@H]([C@@H](O)C(=O)O)C(=O)O.O[C@H]([C@@H](O)C(=O)O)C(=O)O | [CAS DataBase Reference]
65-31-6(CAS DataBase Reference) | [EPA Substance Registry System]
65-31-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T+,N | [Risk Statements ]
R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed .
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S13:Keep away from food, drink and animal feeding stuffs .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 1659 6.1/PG 2
| [WGK Germany ]
2
| [RTECS ]
QT0350000
| [HazardClass ]
6.1(a) | [PackingGroup ]
II | [Storage Class]
6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | [Hazard Classifications]
Acute Tox. 2 Inhalation
Acute Tox. 3 Oral
Aquatic Chronic 2
Eye Irrit. 2
Repr. 2 | [Safety Profile]
Poison by ingestion,
intravenous, intraperitoneal, and
subcutaneous routes. An experimental
teratogen. Experimental reproductive
effects. When heated to decomposition it
emits toxic fumes of NOx and CO. See also
NICOTINE. | [Hazardous Substances Data]
65-31-6(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Uses]
cathartic, laxative | [Uses]
nicotinyl acetylchloline receptor agonist, ectoparasiticide | [General Description]
Potent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions. | [Biological Activity]
Nicotinic acetylcholine receptor (nAChR) agonist (K i values are 1, > 1000, 4000 and 7130 nM at α 4 β 2, α 1 β 1 δ γ , rat α 7 and human α 7 respectively). Exhibits vasoconstrictive, hypertensive and prothrombotic activity in vivo . | [Biochem/physiol Actions]
Product does not compete with ATP. | [storage]
Desiccate at RT |
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