| Identification | Back Directory | [Name]
4′′,5′′-dehydroisopsoralidin | [CAS]
65639-51-2 | [Synonyms]
4′′,5′′-dehydroisopsoralidin
3H,7H-Benzofuro[3,2-c]pyrano[3,2-g][1]benzopyran-7-one, 10-hydroxy-3,3-dimethyl- (9CI) | [Molecular Formula]
C20H14O5 | [MOL File]
65639-51-2.mol | [Molecular Weight]
334.32 |
| Hazard Information | Back Directory | [Uses]
4'',5''-Dehydroisopsoralidin is a β-glucuronidase inhibitor (IC50: 6.3 μM). 4'',5''-Dehydroisopsoralidin has anti-inflammatory and anti-oxidative effects. 4'',5''-Dehydroisopsoralidin can be used in the research of inflammation and cancners[1][2]. | [References]
[1] De-Wu Zhang, et al. Solalyratins A and B, new anti-inflammatory metabolites from Solanum lyratum. J Nat Med. 2012 Apr;66(2):362-6. DOI:10.1007/s11418-011-0581-3
[2] Christian Limper, et al. Compounds isolated from Psoralea corylifolia seeds inhibit protein kinase activity and induce apoptotic cell death in mammalian cells. J Pharm Pharmacol. 2013 Sep;65(9):1393-408. DOI:10.1111/jphp.12107
[3] Tong-Hong Wang, et al. The flavonoid corylin exhibits lifespan extension properties in mouse. Nat Commun. 2022 Mar 9;13(1):1238. DOI:10.1038/s41467-022-28908-2 |
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