| Identification | Back Directory | [Name]
Uridine-5-oxyacetic acid methyl ester | [CAS]
66536-81-0 | [Synonyms]
methyl uridin-5-yloxyacetate
Uridine-5-oxyacetic acid methyl ester
Uridine 5-oxyacetic acid methyl ester,RNA modified nucleoside mcmO5U
Acetic acid, [(1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidinyl)oxy]-, methyl ester | [Molecular Formula]
C12H16N2O9 | [MOL File]
66536-81-0.mol | [Molecular Weight]
332.26 |
| Hazard Information | Back Directory | [Uses]
Uridine 5-oxyacetic acid methyl ester is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [Definition]
ChEBI: A methyl ester that is uridine which is substituted at position 5 on the uracil ring by a methoxycarbonylmethoxy group. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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