| Identification | Back Directory | [Name]
3'-O-Methylquercetin 3-galactoside | [CAS]
6743-92-6 | [Synonyms]
Cacticin
Isorhamnetin 3-galactoside
Isorhamnetin 3-O-galactoside
Isorhamnetol 3-O-galactoside
3'-O-Methylquercetin 3-galactoside
2-(4-Hydroxy-3-methoxyphenyl)-3-(β-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one
3-(β-D-Galactopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 3-(β-D-galactopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-
5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-[(3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one | [Molecular Formula]
C22H22O12 | [MDL Number]
MFCD11656141 | [MOL File]
6743-92-6.mol | [Molecular Weight]
478.4 |
| Chemical Properties | Back Directory | [Melting point ]
267-269℃ | [Boiling point ]
834.4±65.0 °C(Predicted) | [density ]
1.75±0.1 g/cm3 (20 ºC 760 Torr) | [form ]
Solid | [pka]
6.17±0.40(Predicted) | [color ]
Light yellow to yellow | [InChIKey]
CQLRUIIRRZYHHS-VYGHHSHNNA-N | [SMILES]
O=C1C2C(=CC(=CC=2OC(C2C=C(OC)C(O)=CC=2)=C1OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O)O)O |&1:23,26,28,30,r| |
| Hazard Information | Back Directory | [Uses]
Isorhamnetin 3-O-galactoside (Cacticin), a flavonoid glycoside isolated from Artemisia capillaris Thunberg, which ameliorates CCl4-induced hepatic damage by enhancing the anti-oxidative defense system and reducing the inflammatory signaling pathways. Isorhamnetin 3-O-galactoside (Cacticin) has antithrombotic and anti-inflammatory activities[1][2][3]. | [Definition]
ChEBI:Isorhamnetin 3-O-beta-D-galactopyranoside is a glycosyloxyflavone that is isorhamnetin substituted at position 3 by a beta-D-galactosyl residue. It has a role as a metabolite. It is a beta-D-galactoside, a monosaccharide derivative, a glycosyloxyflavone, a monomethoxyflavone and a trihydroxyflavone. It is functionally related to an isorhamnetin and a beta-D-galactose. | [References]
[1] Kim DW, et al. Isorhamnetin-3-O-galactoside Protects against CCl4-Induced Hepatic Injury in Mice. Biomol Ther (Seoul). 2012 Jul;20(4):406-12. DOI:10.4062/biomolther.2012.20.4.406
[2] Kim TH, et al. Anti-inflammatory activities of isorhamnetin-3-O-galactoside against HMGB1-induced inflammatory responses in both HUVECs and CLP-induced septic mice. J Cell Biochem. 2013 Feb;114(2):336-45. DOI:10.1002/jcb.24361
[3] Ku SK, et al. Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside. Food Chem Toxicol. 2013 Mar;53:197-204. DOI:10.1016/j.fct.2012.11.040 |
|
|