| Identification | Back Directory | [Name]
Isorhamnetin 3,7-O-diglucoside | [CAS]
6758-51-6 | [Synonyms]
Isorhamnetin-3,7-diglucoside
Isorhamnetin 3,7-O-diglucoside
Isorhamnetin-3,7-O-β-diglucopyranoside
Isorhamnetin 3,7-O-di-β-D-glucopyranoside
Isorhamnetin 3,7-di-O-β-D-glucopyranoside
isorhamnetin 3,7-O-di-β-D-glucopyranoside | [Molecular Formula]
C28H32O17 | [MDL Number]
MFCD34470953 | [MOL File]
6758-51-6.mol | [Molecular Weight]
640.55 |
| Chemical Properties | Back Directory | [Boiling point ]
1016.2±65.0 °C(Predicted) | [density ]
1.79±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
5.77±0.40(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Isorhamnetin 3,7-di-O-β-D-glucopyranoside, a major flavonoid compound, is metabolized in vivo by intestinal bacteria to isorhamnetin and that isorhamnetin plays an important role as an antioxidant[1]. | [in vivo]
Isorhamnetin 3,7-di-O-β-D-glucopyranoside (10 or 20 mg/kg of body weight/day for 10 days; p.o.) to rats with streptozotocin-induced diabetes significantly reduced serum levels of glucose and 5-(hydroxymethyl)furfural (5-HMF), which is glycosylated with hemoglobin and is an indicator of oxidative stress[1]. | Animal Model: | Male Wistar rats (5 weeks old, 120-130 g) (STZ-induced diabetic rats had higher glucose and 5-HMF levels than normal rats)[1] | | Dosage: | 10 or 20 mg/kg of body weight | | Administration: | P.o.; daily for 10 days | | Result: | The serum glucose levels of rats given 10 and 20 mg of orally were 510.1 and 492.4 mg/dL, respectively, whereas the control level was 574.2 mg/dL.
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| [References]
[1] Yokozawa T, et al. Antioxidant effects of isorhamnetin 3,7-di-O-beta-D-glucopyranoside isolated from mustard leaf (Brassica juncea) in rats with streptozotocin-induced diabetes. J Agric Food Chem. 2002;50(19):5490-5495. DOI:10.1021/jf0202133 |
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