| Identification | Back Directory | [Name]
MARTYNOSIDE | [CAS]
67884-12-2 | [Synonyms]
Martyside
MARTYNOSIDE
3-Hydroxy-4-methoxyphenethyl 3-O-α-L-rhamnopyranosyl-4-O-(3-methoxy-4-hydroxy-trans-cinnamoyl)-β-D-glucopyranoside
1-O-(3-Hydroxy-4-methoxyphenethyl)-3-O-(α-L-rhamnopyranosyl)-β-D-glucopyranose 4-(3-methoxy-4-hydroxy-trans-cinnamate)
2-(3-Hydroxy-4-methoxyphenyl)ethyl 3-O-(α-L-rhamnopyranosyl)-4-O-[(E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl]-β-D-glucopyranoside
β-D-Glucopyranoside, 2-(3-hydroxy-4-methoxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 4-[(2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoate]
(2R,3R,4R,5R,6R)-5-hydroxy-6-[2-(3-hydroxy-4-methoxyphenyl)ethoxy]-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl](E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate | [Molecular Formula]
C31H40O15 | [MDL Number]
MFCD11111293 | [MOL File]
67884-12-2.mol | [Molecular Weight]
652.64 |
| Chemical Properties | Back Directory | [Boiling point ]
865.1±65.0 °C(Predicted) | [density ]
1.48±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
9.73±0.31(Predicted) | [color ]
White to off-white | [Cosmetics Ingredients Functions]
SKIN PROTECTING
ANTIOXIDANT
SKIN CONDITIONING | [InChIKey]
WLWAYPFRKDSFCL-OQPPUVGONA-N |
| Hazard Information | Back Directory | [Uses]
Martynoside protects ex vivo bone marrow cells from 5-fluorouracil (5-FU)-induced cell death and inflammation response by down-regulating the TNF signaling pathway[1].Martynoside is a potent antiestrogen in MCF-7 cells, increasing IGFBP3 levels | [target]
Estrogen receptor | ROS | Progestogen receptor | [References]
[1] Hong M, et al. Ex vivo and in vivo chemoprotective activity and potential mechanism of Martynoside against 5-fluorouracil-induced bone marrow cytotoxicity.?Biomed Pharmacother. 2021;138:111501. DOI:10.1016/j.biopha.2021.111501
[2] Papoutsi Z,et al. Acteoside and martynoside exhibit estrogenic/antiestrogenic properties.?J Steroid Biochem Mol Biol. 2006;98(1):63-71. DOI:10.1016/j.jsbmb.2005.07.005 |
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