| Identification | Back Directory | [Name]
Carbadox | [CAS]
6804-07-5 | [Synonyms]
CBX
M31
MOD1
gs6244
Mecadox
CARBADO
p25beta
CARBADOX
karbadox
fortigro
getroxel
HP1-BETA
carabadox
Mecadox-S
LABOTEST-BB LT00771878
2-formylquinoxaline1,4-dioxidecarbomethoxyhydrazone
3-(2-chinoxalinylmethylen-1,4-dioxid)methylkarbazat
hydrazinecarboxylicacid,(2-quinoxalinylmethylene)-,me
Methyl-3-(2-quinoxanylmethylene)carbazate-N,N'-dioxide
2-(2-quinoxalinyl methylene) hydrazine carboxylic acid
methyl 3-(quinoxalin-2-ylmethylene)carbazate 1,4-dioxide
methyl3-(2-quinoxalinylmethylene)carbazate-n1,n4-dioxide
2-(methoxycarbonylhydrazonomethyl)quinoxaline 1,4-dioxide
Methyl-3-(2'-quinoxalinylmethylene) carbazate-N,N-dioxide
3-(2-chinoxalinylmethylen-1,4-dioxid)methylkarbazat fortigro
3-[2-QUINOXALINYLMETHYLENE]CARBAZIC ACID METHYL ESTER N,N'-DIOXIDE
(E)-2-((2-(Methoxycarbonyl)hydrazono)methyl)quinoxaline 1,4-dioxide
hydrazinecarboxylicacid,(2-quinoxalinylmethylene)-,methylester,n,n’-diox
carbazicacid,3-(2-quinoxalinylmethylene)-,methylester,n(sup1),n(sup4)-di
Hydrazinecarboxylicacid,(2-quinoxalinylmethylene)-,methylester,N,N’-dioxide
Carbadox,3-(2-Quinoxalinylmethylene)carbazic acid methyl ester N,N′-dioxide
(2-Quinoxalinylmethylene)hydrazinecarboxylic Acid Methyl Ester N,N'-Dioxide
Hydrazinecarboxylic acid, (1,4-dioxido-2-quinoxalinyl)methylene-, methyl ester
2-(2-quinoxalinylmethylene)hydrazine-carboxylic acid methyl ester n,n'-dioxide
Methyl 3-[2-quinoxalinylmethylene] carbazate N1,N4-dioxide
Hydrazinecarboxylicacid, 2-[(1,4-dioxido-2-quinoxalinyl)Methylene]-, Methyl ester
carbadox (INN) methyl 3-(quinoxalin-2-ylmethylene)carbazate 1,4-dioxide 2-(methoxycarbonylhydrazonomethyl)quinoxaline 1,4-dioxide | [EINECS(EC#)]
229-879-0 | [Molecular Formula]
C11H10N4O4 | [MDL Number]
MFCD00057293 | [MOL File]
6804-07-5.mol | [Molecular Weight]
262.22 |
| Chemical Properties | Back Directory | [Appearance]
Yellow Crystalline Solid | [Melting point ]
239-240°C | [Boiling point ]
405.47°C (rough estimate) | [density ]
1.3602 (rough estimate) | [refractive index ]
1.6000 (estimate) | [Fp ]
18°(64°F) | [storage temp. ]
2-8°C
| [solubility ]
DMSO (Slightly, Sonicated) | [form ]
powder | [pka]
10.51±0.46(Predicted) | [color ]
Yellow to Dark Yellow | [Water Solubility ]
Soluble in 1N NaOH (50 mg/ml), and water (partly). | [Henry's Law Constant]
2.2×1017 mol/(m3Pa) at 25℃, HSDB (2015) | [Stability:]
Light Sensitive | [InChI]
1S/C11H10N4O4/c1-19-11(16)13-12-6-8-7-14(17)9-4-2-3-5-10(9)15(8)18/h2-7H,1H3,(H,13,16)/b12-6+ | [InChIKey]
OVGGLBAWFMIPPY-WUXMJOGZSA-N | [SMILES]
COC(=O)N\N=C\c1cn(=O)c2ccccc2n1=O | [CAS DataBase Reference]
6804-07-5 | [EPA Substance Registry System]
Hydrazinecarboxylic acid, 2-[(1,4-dioxido-2-quinoxalinyl)methylene]-, methyl ester (6804-07-5) |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Crystalline Solid | [Uses]
Antimicrobial | [Originator]
Carbadox,Agrimex | [Definition]
ChEBI: Carbadox is a quinoxaline derivative. | [Manufacturing Process]
A solution of methylcarbazate (48.0 mg) in methanol (250 ml) is added all at
once at room temperature to a well stirred solution of 2-formylquinoxaline-
1,4-dioxide (100 g) in methanol (2.5 liters). Two drops of concentrated
hydrochloric acid are added. The mixture is stirred for 3 hours then filtered to remove the yellow crystalline product. The crystals of (2-
quinoxalinylmethylene)hydrazinecarboxylic acid methyl ester are washed with
methanol then air dried; M.P. 234.5-236°C (dec.). Yield=121.8 g. The product
is purified by refluxing in chloroform for 2 hours, followed by filtration and air
drying; M.P. 239.5-240°C (dec.).
The ultraviolet absorption spectrum (water) exhibits maxima at 236, 251,
303, 366 and 373 nm with extinction coefficients of 11,000, 10,900, 36,400,
16,100 and 16,200, respectively. | [Brand name]
Mecadox (Pfizer). | [Therapeutic Function]
Antibacterial | [Biochem/physiol Actions]
Carbadox is a quinoxaline-di-N-oxide antibiotic that is generally used in feed to swine to prevent dysentery and improve feed efficiency. It inhibits bacteria by intercalation and induction of mutations in bacterial genome. | [storage]
Store at -20°C |
| Safety Data | Back Directory | [Hazard Codes ]
F,T | [Risk Statements ]
45-11-22 | [Safety Statements ]
53-45 | [RIDADR ]
UN 1325 4.1/PG 2 | [WGK Germany ]
3
| [RTECS ]
FE2779000
| [HazardClass ]
4.1 | [HS Code ]
29339900 | [Storage Class]
4.1B - Flammable solid hazardous materials | [Hazard Classifications]
Acute Tox. 4 Oral
Carc. 1B
Flam. Sol. 1 | [Safety Profile]
Moderately toxic by
ingestion. Questionable carcinogen with
experimental carcinogenic effects. Human
mutation data reported. When heated to
decomposition it emits toxic fumes of Nox. | [Hazardous Substances Data]
6804-07-5(Hazardous Substances Data) |
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
|