| Identification | More | [Name]
Diethylacetamide | [CAS]
685-91-6 | [Synonyms]
ACETIC ACID DIETHYLAMIDE
ACETYL DIETHYLAMINE
diethylacetamide
N-ACETYLDIETHYLAMINE
N,N-DIETHYLACETAMIDE
acetamide,n,n-diethyl-
acetamine,n,n-diethyl-
aceticacid,amide,n,n-diethyl
CH3CON(C2H5)2
n,n-diaethylacetamid
n,n-diethyl-acetamid
N,N-Diethylacetamide,99%
N,N-Diethylethanamide | [EINECS(EC#)]
211-685-2 | [Molecular Formula]
C6H13NO | [MDL Number]
MFCD00009047 | [Molecular Weight]
115.17 | [MOL File]
685-91-6.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless liquid | [Melting point ]
<20 °C | [Boiling point ]
182-186 °C (lit.) | [density ]
0.925 g/mL at 25 °C(lit.)
| [vapor pressure ]
1.2 hPa (25 °C) | [refractive index ]
n20/D 1.440(lit.)
| [Fp ]
159 °F
| [storage temp. ]
Store below +30°C. | [solubility ]
53.5g/l | [form ]
clear liquid | [pka]
-0.41±0.70(Predicted) | [color ]
Colorless to Almost colorless | [Water Solubility ]
Soluble in water. | [BRN ]
1209428 | [Dielectric constant]
31.329999999999998 | [CAS DataBase Reference]
685-91-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Acetamide, N,N-diethyl-(685-91-6) | [EPA Substance Registry System]
685-91-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [WGK Germany ]
3
| [RTECS ]
AB7000000
| [TSCA ]
Yes | [HS Code ]
29241900 | [Safety Profile]
Moderately toxic by
ingestion and intraperitoneal routes.
Questionable carcinogen with experimental
tumorigenic data. Flammable when exposed
to heat or flame. To fight fire, use foam,
mist, CO2, dry chemical. When heated to
decomposition it emits toxic fumes of NOx. | [Hazardous Substances Data]
685-91-6(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: 1500 mg/kg |
| Hazard Information | Back Directory | [Hazard]
Toxic by ingestion. | [Chemical Properties]
clear colorless liquid | [Uses]
N,N-Diethylacetamide was used to investigate the spectroscopic properties ofN,N-diethyl-2-[(4-substituted)phenylsulfinyl] acetamides. It is commonly used as drug solvent. | [Synthesis Reference(s)]
Chemistry Letters, 18, p. 1983, 1989
The Journal of Organic Chemistry, 59, p. 4035, 1994 DOI: 10.1021/jo00094a004 | [General Description]
N,N-Diethylacetamide is commonly used as drug solvent. | [Purification Methods]
Dissolve the amide in cyclohexane, shake with anhydrous BaO and then filter. The procedure is repeated three times, and the cyclohexane is distilled off at atmospheric pressure. The crude amide is also fractionally distilled three times from anhydrous BaO. [Beilstein 4 III 349.] |
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