| Identification | More | [Name]
2-Methylindoline | [CAS]
6872-06-6 | [Synonyms]
2,3-DIHYDRO-2-METHYLINDOLE
2-METHYL-2,3-DIHYDRO-1H-INDOLE
2-METHYLINDOLINE
(R,S)-2-Methyl-2,3-dihydro-1H-indole
1H-Indole, 2,3-dihydro-2-methyl-
1H-Indole,2,3-dihydro-2-methyl-
2,3-dihydro-2-methyl-1h-indol
2,3-Dihydro-2-methyl-1H-indole
2-Methyl-2,3-dihydroindole
2-methyl-indolin
alpha-Methyldihydroindole
Dihydroindole, 2-methyl-
Indoline, 2-methyl-
PE-11
2-Methylindoline, 99+% | [EINECS(EC#)]
229-971-0 | [Molecular Formula]
C9H11N | [MDL Number]
MFCD00005706 | [Molecular Weight]
133.19 | [MOL File]
6872-06-6.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR YELLOW TO BROWN LIQUID | [Melting point ]
-51 °C
| [Boiling point ]
228-229 °C (lit.) | [density ]
1.023 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.569(lit.)
| [Fp ]
200 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform, Methanol | [form ]
Liquid | [pka]
5.26±0.40(Predicted) | [color ]
Clear yellow to brown | [Specific Gravity]
1.02 | [Optical Rotation]
-2.4550° (C=1.0 g/100ml, MEOH, 20°C, 589nm) | [Water Solubility ]
negligible | [InChI]
1S/C9H11N/c1-7-6-8-4-2-3-5-9(8)10-7/h2-5,7,10H,6H2,1H3 | [InChIKey]
QRWRJDVVXAXGBT-UHFFFAOYSA-N | [SMILES]
CC1Cc2ccccc2N1 | [CAS DataBase Reference]
6872-06-6(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Methylindoline(6872-06-6) | [EPA Substance Registry System]
6872-06-6(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS06,GHS09 | [Signal word ]
Danger | [Hazard statements ]
H302-H311-H319-H400 | [Precautionary statements ]
P264-P273-P280-P301+P312-P302+P352+P312-P305+P351+P338 | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S60:This material and/or its container must be disposed of as hazardous waste .
S57:Use appropriate container to avoid environmental contamination . | [WGK Germany ]
3
| [RTECS ]
NM1926350
| [Hazard Note ]
Irritant | [TSCA ]
TSCA listed | [HS Code ]
29349990 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Dermal
Acute Tox. 4 Oral
Aquatic Acute 1
Eye Irrit. 2 |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR YELLOW TO BROWN LIQUID | [Uses]
Reactant for preparation of:
- Inhibitors of NOD1-induced nuclear factor-κB activation
- Red fluorescent dyes for organic light-emitting diodes
- Norepinephrine reuptake inhibitors
- MT2-selective melatonin receptor antagonists
- Protease-activated receptor-1 antagonists
- Diuretic agent indapamide
- Dopamine D2/D4 receptor antagonists
- Antitumor agents
| [Uses]
2-Methylindoline is an intermediate in the production of various indole derivatives | [Definition]
ChEBI: 2-Methylindoline is a member of indoles. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 111, p. 4108, 1989 DOI: 10.1021/ja00193a056
Chemical and Pharmaceutical Bulletin, 26, p. 108, 1978 DOI: 10.1248/cpb.26.108 |
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