| Identification | More | [Name]
(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine | [CAS]
68737-65-5 | [Synonyms]
(1R,2R)-(-)-1,2-BIS(METHYLAMINO)CYCLOHEXANE
(1R,2R)-1,2-BIS(METHYLAMINO)CYCLOHEXANE
(1R,2R)-DIAMINOMETHYLCYCLOHEXANE
(1R,2R)-N,N'-DIMETHYL-1,2-CYCLOHEXANEDIAMINE
(1R,2R)-(-)-N,N'-DIMETHYLCYCLOHEXANE-1,2-DIAMINE
(R,R)-N,N'-DIMETHYLCYCLOHEXAN-1,2-DIAMINE
TRANS-(1R,2R)-N,N'-BISMETHYL-1,2-CYCLOHEXANE DIAMINE
TRANS-(1R, 2R)-N,N'-DIMETHYL-CYCLOHEXANE-1,2-DIAMINE
(R,R)-(-)-N,N'-Dimethyl-1,2-cyclohexandiamine
(R,R)-1,2-Bis(methylamino)cyclohexane.
N,N'-Dimethyl-cyclohexane-1,2-diamine
trans-(1R,2R)-N,N'-Bismethyl-1,2-cyclohexane
(R,R)-(-)-N,N'-Dimethyl-1,2-diaminocyclohexane
(R,R)-(-)-N,N''-DIMETHYL-1,2-CYCLOHEXANEDIAMINE
(R,R)-(-)-N,N'-Dimethyl-1,2-cyclohexanediamine
(1S,2S)-N1,N2-dimethylcyclohexane-1,2-diamine
trans-1,2-Bis(methylamino)cyclohexane, (R,R)-(-)-N,Nμ-Dimethyl-1,2-diaminocyclohexane | [Molecular Formula]
C8H18N2 | [MDL Number]
MFCD00671527 | [Molecular Weight]
142.24 | [MOL File]
68737-65-5.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
39-44 °C | [alpha ]
-145 º (c=4.47 in chloroform) | [Boiling point ]
249.85°C (rough estimate) | [density ]
0.902 | [refractive index ]
-140 ° (C=4, CHCl3) | [Fp ]
74 °C | [storage temp. ]
0-6°C | [form ]
Low Melting Solid | [pka]
11.04±0.40(Predicted) | [color ]
White to light yellow | [Optical Rotation]
[α]/D -145±5°, c = 4.47 in chloroform | [InChI]
InChI=1S/C8H18N2/c1-9-7-5-3-4-6-8(7)10-2/h7-10H,3-6H2,1-2H3/t7-,8-/m1/s1 | [InChIKey]
JRHPOFJADXHYBR-HTQZYQBOSA-N | [SMILES]
[C@@H]1(NC)CCCC[C@H]1NC | [CAS DataBase Reference]
68737-65-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns.
R22:Harmful if swallowed. | [Safety Statements ]
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S25:Avoid contact with eyes .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
3259 | [WGK Germany ]
3 | [HazardClass ]
8 | [PackingGroup ]
Ⅱ | [HS Code ]
29213000 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Dam. 1
Skin Corr. 1B |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
(R,R)-(?)-N,N′-Dimethyl-1,2-cyclohexanediamine can be used:
- As a ligand in the preparation of 4H-benzo[f]imidazo[1,4]diazepin-6-one through multi-component Ullmann coupling reaction.
- In one of the key synthetic steps for the preparation of tricyclic γ-secretase modulators.
- To prepare chiral fluorous diamino-diol proligand, which is used in the synthesis of zirconium metal complexes applicable as catalysts in 1-hexene polymerization.
| [General Description]
(R,R)-(-)-N,N′-Dimethyl-1,2-cyclohexanediamine is a N,N′-dimethylated derivative of enantiopure 1,2-diaminocyclohexane. It can be formed during the hydrolysis of (R3a,R7a)-1,3-(dimethyl)-2-phenyl-2,3,3a,4,5,6,7,7a-octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide using HCl-methanol. |
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