| Identification | More | [Name]
2-Methylimidazole | [CAS]
693-98-1 | [Synonyms]
2-Methyl-1H-imidazole
2-METHYLGLYOXALINE
2-METHYLIMIDAZOLE
2MI
AKOS BBS-00004447
RESICURE(TM) 46
1H-Imidazole,2-methyl-
2-methyl-1h-imidazol
2-methyl-imidazol
2MZ
Glyoxalethyline
Imidazole, 2-methyl-
p-Oxal-methyline
Flucythrinate PESTANAL
2-Methylimidazole,97%
2-METHYLIMIDAZOLE pure
Curezol 2MZ
Denka CN 25 | [EINECS(EC#)]
211-765-7 | [Molecular Formula]
C4H6N2 | [MDL Number]
MFCD00005190 | [Molecular Weight]
82.1 | [MOL File]
693-98-1.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystalline powder | [Melting point ]
142-143 °C (lit.) | [Boiling point ]
267-268 °C (lit.) | [density ]
1.0500 (rough estimate) | [vapor pressure ]
<1 mm Hg ( 0 °C)
| [refractive index ]
1.4970 (estimate) | [Fp ]
155 °C
| [storage temp. ]
2-8°C | [solubility ]
780g/l | [form ]
Crystalline Powder | [pka]
14.44±0.10(Predicted) | [color ]
White to light yellow | [PH]
10.5-11.5 (100g/l, H2O, 20℃) | [PH Range]
10.5 | [Water Solubility ]
Soluble in water and ethanol. | [BRN ]
1368 | [InChIKey]
LXBGSDVWAMZHDD-UHFFFAOYSA-N | [LogP]
0.22 at 25℃ | [CAS DataBase Reference]
693-98-1(CAS DataBase Reference) | [IARC]
2B (Vol. 101) 2013 | [NIST Chemistry Reference]
1H-Imidazole, 2-methyl-(693-98-1) | [EPA Substance Registry System]
693-98-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R22:Harmful if swallowed.
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S25:Avoid contact with eyes . | [RIDADR ]
UN 3259 8/PG 2
| [WGK Germany ]
2
| [RTECS ]
NI7175000
| [Autoignition Temperature]
>600 °C DIN 51794 | [Hazard Note ]
Harmful/Corrosive | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29332990 | [Hazardous Substances Data]
693-98-1(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: 1500 mg/kg |
| Hazard Information | Back Directory | [Hazard]
Possible carcinogen. | [Chemical Properties]
2-Methylimidazole is a white to light yellow crystalline powder with an amine-like odor. It is highly soluble in polar organic solvents. | [Uses]
2-Methylimidazole is a monomethylated imidazole that can be used as a building block in the preparation of a wide range of biologically active compounds. 2-Methylimidazole as well as other imidazoles
can be use as catalyst for refolding of enhanced coloured fluorescent protein. 2-Methylimidazole has been identified as a byproduct of fermentation and is detected in foods and mainstream and side-str
eam tobacco smoke. | [Uses]
Hardener or accelerator for epoxy | [Preparation]
2-Methylimidazole is prepared by condensation of glyoxal, ammonia and acetaldehyde, a Radziszewski reaction. It is widely used as a polymeriza tion cross-linking accelerator and a hardener for epoxy resin systems for semiconductor potting compounds and soldering masks.
It is obtained by eliminating dehydrogenation of 2-methylimidazoline. 2-methylimidazoline heated to melt (melting point 107 ℃), carefully add active nickel, raise the temperature to 200-210 ℃ reaction 2h. cool down to below 150 ℃, add water to dissolve, while hot pressure filtration, separation of active nickel, the filter Chemicalbook liquid concentrated to a temperature of 140 ℃ or more, put the material cooling that 2-methylimidazole. Use the method to produce purity of ≥ 98% of the product, 1t product consumption of ethylenediamine (95%) 1095kg, acetonitrile 975kg. better method is to use glyoxal and aldehyde as raw materials. | [General Description]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. | [Flammability and Explosibility]
Notclassified | [Purification Methods]
Recrystallise 2-methylimidazole from *benzene or pet ether. The picrate has m 215o (from H2O). [Beilstein 23 III/IV 594, 23/5 V 35.] | [References]
[1] Hachu?a B, et al. Crystal and Molecular Structure Analysis of 2-Methylimidazole. Journal of Chemical Crystallography, 2009; 40: 201–206. |
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