| Identification | Back Directory | [Name]
15(S)-HETE SOLUTION | [CAS]
71030-36-9 | [Synonyms]
15(S)-HETE SOLUTION
(5Z,8Z,11Z,13E)-15-HETE
(±)15-HETE MaxSpec Standard
5,8,11,13-Eicosatetraenoic acid, 15-hydroxy-, (5Z,8Z,11Z,13E)-
15(S)-Hydroxy-5(Z),8(Z),11(Z),13(E)-eicosatetraenoic acid [15(S)-HETE | [Molecular Formula]
C20H32O3 | [MDL Number]
MFCD00216113 | [MOL File]
71030-36-9.mol | [Molecular Weight]
320.47 |
| Chemical Properties | Back Directory | [Boiling point ]
487.7±45.0 °C(Predicted) | [density ]
0.984±0.06 g/cm3(Predicted) | [Fp ]
10℃ (tag closed test) | [solubility ]
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS ph 7.2: 0.8 mg/ml | [form ]
Liquid | [pka]
4.75±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
(±)15-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)15-HETE is similar to that of its constituent enantiomers (Item Nos. 34720 and 34710).
(±)15-HETE MaxSpec® standard is a quantitative grade standard of (±)15-HETE (Item No. 34700) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This (±)15-HETE MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality. | [Uses]
(±)15-HETE is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [Definition]
ChEBI: A HETE that is (5Z,8Z,11Z,13E)-15-hydroxyicosa-5,8,11,13-tetraenoic acid bearing a hydroxy substituent at position 15. | [IC 50]
Alkyl-Chain | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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Alfa Chemistry
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1-516-6625404 |
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https://www.alfa-chemistry.com |
| Company Name: |
Enzo Biochem Inc
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| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
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