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71030-38-1

71030-38-1 Structure

71030-38-1 Structure
IdentificationBack Directory
[Name]

GCZRCCHPLVMMJE-RLZWZWKOSA-N
[CAS]

71030-38-1
[Synonyms]

GCZRCCHPLVMMJE-RLZWZWKOSA-N
5,8,12,14-Eicosatetraenoic acid, 11-hydroxy-, (5Z,8Z,12E,14Z)-
[Molecular Formula]

C20H32O3
[MDL Number]

MFCD00065825
[MOL File]

71030-38-1.mol
[Molecular Weight]

320.47
Chemical PropertiesBack Directory
[solubility ]

0.1 M Na2CO3: 2 mg/ml
DMF: Miscible
DMSO: Miscible
Ethanol: MisciblePBS pH 7.2: 0.8 mg/ml
Hazard InformationBack Directory
[Uses]

1,2-Di-O-hexadecyl-sn-glycero-3-phosphatidylethanolamine is an ester product.
[Definition]

ChEBI: 11-HETE is a HETE that is (5Z,8Z,12E,14Z)-icosa-5,8,12,14-tetraenoic acid substituted at position 11 by a hydroxy group. It has a role as a mouse metabolite. It is functionally related to an icosa-5,8,12,14-tetraenoic acid. It is a conjugate acid of an 11-HETE(1-).
[References]

[1] WILLIAM S. POWELL  Joshua R. Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid[J]. Biochimica et biophysica acta. Molecular and cell biology of lipids, 2015, 1851 4: Pages 340-355. DOI: 10.1016/j.bbalip.2014.10.008
[2] PRISCILLA BENTO MATOS CRUZ DEROGIS  Sayuri M  Adriano B Chaves Fillho. Characterization of Hydroxy and Hydroperoxy Polyunsaturated Fatty Acids by Mass Spectrometry.[J]. Advances in experimental medicine and biology, 2019, 1127: 21-35. DOI: 10.1007/978-3-030-11488-6_2
[3] GUIDO D.M.  Mathews W R  Mckenna R. Quantitation of Hydroperoxy-Eicosatetraenoic Acids and Hydroxy-Eicosatetraenoic Acids as Indicators of Lipid Peroxidation Using Gas Chromatography-Mass Spectrometry[J]. Analytical biochemistry, 1993, 209 1: Pages 123-129. DOI: 10.1006/abio.1993.1091
[4] R.D.R. CAMP. The identification of hydroxy fatty acids in psoriatic skin[J]. Prostaglandins, 1983, 26 3: Pages 431-447. DOI: 10.1016/0090-6980(83)90178-8
[5] EMMA WADDINGTON . Identification and Quantitation of Unique Fatty Acid Oxidation Products in Human Atherosclerotic Plaque Using High-Performance Liquid Chromatography[J]. Analytical biochemistry, 2001, 292 2: Pages 234-244. DOI: 10.1006/abio.2001.5075
[6] DONG CHENG. MGAT2 inhibitor decreases liver fibrosis and inflammation in murine NASH models and reduces body weight in human adults with obesity.[J]. Cell metabolism, 2022, 34 11: 1732-1748.e5. DOI: 10.1016/j.cmet.2022.10.007
[7] YILIN PANG . LC−MS/MS-based arachidonic acid metabolomics in acute spinal cord injury reveals the upregulation of 5-LOX and COX-2 products[J]. Free Radical Biology and Medicine, 2022, 193: Pages 363-372. DOI: 10.1016/j.freeradbiomed.2022.10.303
[8] ANNE-SOPHIE ARCHAMBAULT. High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients[J]. FASEB Journal, 2021, 35 6. DOI: 10.1096/fj.202100540r
[9] DAVID MERIWETHER. Apolipoprotein A-I mimetics mitigate intestinal inflammation in COX2-dependent inflammatory bowel disease model.[J]. Journal of Clinical Investigation, 2019, 129 9: 3670-3685. DOI: 10.1172/jci123700
[10] CARLOS ARTÉRIO SORGI. Comprehensive high-resolution multiple-reaction monitoring mass spectrometry for targeted eicosanoid assays[J]. Scientific Data, 2018, 5 1: 1-12. DOI: 10.1038/sdata.2018.167
[11] JAMIE L LAHVIC. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 37: 9252-9257. DOI: 10.1073/pnas.1806077115
[12] SANDRA GOUVEIA-FIGUEIRA. Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor.[J]. PLoS ONE, 2015: e0139212. DOI: 10.1371/journal.pone.0139212
[13] ALWENA H MORGAN. Quantitative assays for esterified oxylipins generated by immune cells[J]. Nature Protocols, 2010, 5 12: 1919-1931. DOI: 10.1038/nprot.2010.162
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