| Identification | More | [Name]
3-COUMARANONE | [CAS]
7169-34-8 | [Synonyms]
2,3-DIHYDROBENZO[B]FURAN-3-ONE
3(2H)-BENZOFURANONE
3-COUMARANONE
BENZOFURAN-3(2H)-ONE
BENZOFURAN-3(2H)-ONE, 3-COUMARANONE
BENZOFURAN-3-ONE
COUMARANONE
3-Coumaranone(3(2H)-Benzofuranone)
(2H)-Benzofuran-3-one
2,3-dihydro-1-benzofuran-3-one
Coumaran-3-one
2,3-Dihydrobenzofuran-3-one
3-Oxocoumaran | [EINECS(EC#)]
640-279-1 | [Molecular Formula]
C8H6O2 | [MDL Number]
MFCD00051810 | [Molecular Weight]
134.13 | [MOL File]
7169-34-8.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
101-103 °C | [Boiling point ]
207.23°C (rough estimate) | [density ]
1.1603 (rough estimate) | [refractive index ]
1.4800 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Store in freezer, under -20°C | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [color ]
Yellow to Dark Yellow | [Water Solubility ]
Slightly miscible with water. | [Sensitive ]
Light Sensitive | [BRN ]
115296 | [InChI]
InChI=1S/C8H6O2/c9-7-5-10-8-4-2-1-3-6(7)8/h1-4H,5H2 | [InChIKey]
MGKPCLNUSDGXGT-UHFFFAOYSA-N | [SMILES]
O1C2=CC=CC=C2C(=O)C1 | [CAS DataBase Reference]
7169-34-8(CAS DataBase Reference) | [NIST Chemistry Reference]
3(2H)-benzofuranone(7169-34-8) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H332-H335 | [Precautionary statements ]
P261-P280-P305+P351+P338 | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
4.5-9 | [Hazard Note ]
Irritant | [HS Code ]
29329990 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
3-Coumaranone is used in the aurones, [2-benzylidenebenzofuran-3(2H)-ones] by reacting with appropriate aldehyde. It is involved in the condensation reaction with aldehydes in the presence of morpholine acetate to prepare substituted 2-(arylidene)benzofuran-3(ZH)-ones. In Horner-Wadsworth-Emmons reaction, it reacts with diethyl? cyanomethyl?phosphonate to give 3-(cyanomethyl)benzofurans, which is an intermediate in the synthesis of antihyperglycemic agents. | [General Description]
Benzofuran-3(2H)-one undergoes condensation with aldehydes in the presence of morpholine acetate to yield substituted 2-(arylidene)benzofuran-3(ZH)-ones. It undergoes acid- or base-catalyzed condensation with an appropriate aldehyde to yield aurones [2-benzylidenebenzofuran-3(2H)-ones]. | [Synthesis]
At room temperature and pressure, 0.2 mmol of 2-ethynylphenol was dissolved in 1 mL of dichloromethane to obtain a dichloromethane solution of 2-ethynylphenol; then 0.01 mmol of mercury trifluoromethanesulfonate and 0.24 mmol of pyridine-N-oxide were adde |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
| Company Name: |
Shanghai Ennopharm Co., Ltd.
|
| Telephone: |
+86 (21) 6435-5022 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList13640/0_EN.htm |
|