| Identification | Back Directory | [Name]
R(-)-DENOPAMINE | [CAS]
71771-90-9 | [Synonyms]
kalgut
TA 064
Carguto
DENOPAMINE
TA-064：Carguto
R(-)-DENOPAMINE
[(βR)-β,4-Dihydroxyphenethyl](3,4-dimethoxyphenethyl)amine
(R)-1-(4-Hydroxyphenyl)-2-(3,4-dimethoxyphenethylamino)ethanol
(-)-α-(3,4-dimethoxyphenethylaminomethyl)-4-hydroxy-benzyl-alcohol
(-)-(r)-1-(p-hydroxyphenyl)-2-((3,4-dimethoxyphenethyl)amino)ethanol
(-)-ALPHA-(3,4-DIMETHOXYPHENETHYLAMINOMETHYL)-4-HYDROXYBENZYLALCOHOL
- α-[[[2-(3，4-Dimethoxyphenyl)ethyl]amino]methyl]-4-hydroxyben-zenemethanol
alpha-(((2-(3,4-dimethoxyphenyl)ethyl)amino)methyl)-4-hydroxy-benzenemethano
(R)-α-[[[2-(3,4-Dimethoxyphenyl)ethyl]amino]methyl]-4-hydroxybenzenemethanol
(αR)-α-[[[2-(3,4-Dimethoxyphenyl)ethyl]amino]methyl]-4-hydroxybenzenemethanol
Benzenemethanol, α-[[[2-(3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-hydroxy-, (R)-
Benzenemethanol, α-[[[2-(3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-hydroxy-, (αR)- | [Molecular Formula]
C18H23NO4 | [MDL Number]
MFCD00867122 | [MOL File]
71771-90-9.mol | [Molecular Weight]
317.38 |
| Chemical Properties | Back Directory | [Melting point ]
135°C | [Boiling point ]
456.67°C (rough estimate) | [density ]
1.1949 (rough estimate) | [refractive index ]
1.5740 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
DMSO: 26 mg/mL, soluble
| [form ]
powder
| [pka]
9.97±0.26(Predicted) | [color ]
white
|
| Hazard Information | Back Directory | [Description]
Denopamine is a potent orally-active cardiotonic with selective effects on the beta,
adrenergic receptors. Unlike isoproterenol or dobutamine, denopamine’s positive
inotropic activity is not mediated through the release of catecholamines; its lack of effect
on heart rate and myocardial oxygen consumption thus offers significant advantages in the
management of congestive heart failure. | [Chemical Properties]
L-hydrochloride: C18H23NO4·HCl. Crystallizes from isopropanol, melting point 138-139.5°C. [α]D23-38° (C=1, methanol). DL-hydrochloride: C18H23NO4·HCl. Crystallizes from isopropanol-isopropyl ether, melting point 164-167°C. | [Originator]
Tanabe Seiyaku (Japan) | [Uses]
R(-)-Denopamine has been used as an β-adrenergic agonist to study its effects on contractility in isolated lymphatic vessels (LVs). | [Definition]
ChEBI:Denopamine is a dimethoxybenzene. | [Brand name]
Kalgut | [Biochem/physiol Actions]
Denopamine is a cardiotonic drug. | [storage]
Store at -20°C |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Wuhan Topule
|
| Telephone: |
+86-02787215551 19945035818 |
| Website: |
http://www.topule.com/ |
|