| Hazard Information | Back Directory | [Description]
Brl 22321 is a mast cell stabilizer. | [Uses]
BRL 22321 free base is a stabilizer with similar mast cell stabilizing activity to Cromolyn sodium (HY-B0320A) and also has some smooth muscle relaxant activity. BRL 22321 free base is more potent than Cromolyn sodium (HY-B0320A) in inhibiting rat passive cutaneous and peritoneal anaphylaxis and antigen-induced histamine release from passively sensitized rat peritoneal cells[1]. | [References]
[1] Spicer, et al. "BRL 22321, a compound that has mast cell stabilizing activity similar to that of disodium cromoglycate and in addition has smooth muscle relaxing activity." Agents and Actions 13 (1983): 301-309. DOI:10.1007/BF01971481 |
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