ChemicalBook--->CAS DataBase List--->72492-12-7

72492-12-7

72492-12-7 Structure

72492-12-7 Structure
IdentificationBack Directory
[Name]

SPIZOFURONE
[CAS]

72492-12-7
[Synonyms]

Maon
AG-629
Ccris 1922
SPIZOFURONE
Brn 5334898
Spizofuronum
Espizofurona
Espizofurona [spanish]
5-Acetylspim[benzofuran-2(3H)-1’-cyclopropan]-3-one
5-Acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one
Spiro(benzofuran-2(3H),1'-cyclopropan)-3-one, 5-acetyl-
[Molecular Formula]

C12H10O3
[MDL Number]

MFCD00866749
[MOL File]

72492-12-7.mol
[Molecular Weight]

202.21
Chemical PropertiesBack Directory
[Melting point ]

102-104° (Kawada); mp 106-107° (Watanabe)
[Boiling point ]

280.32°C (rough estimate)
[density ]

1.2076 (rough estimate)
[refractive index ]

1.5080 (estimate)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Acetic anhydride-->p-Toluenesulfonic acid-->2-N-BUTOXYETHYL METHACRYLATE-->Methyl salicylate-->ESTRONE(RG)-->2-Bromo-4-butanolide
Hazard InformationBack Directory
[Description]

Spizofurone is an antiulcer agent that acts primarily by increasing mucus secretion and microcirculation in gastric mucosa and also by its inhibitory effect on acid secretion.
[Chemical Properties]

Crystallized from ethanol, melting point 102-104°C; 106-107°C. Acute toxicity LD50 for male and female mice, male and female rats (mg/kg): 1810, 1740, 5630, 5640 oral.
[Originator]

Takeda (Japan)
[Definition]

ChEBI: Spizofurone is a member of benzofurans.
[Brand name]

Maon
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