ChemicalBook--->CAS DataBase List--->73581-79-0

73581-79-0

73581-79-0 Structure

73581-79-0 Structure
IdentificationBack Directory
[Name]

1,2,3,4-tetrahydro-2-methyl-1,4-dioxonaphthalene-2-sulphonic acid, compound with nicotin-3-amide (1:1)
[CAS]

73581-79-0
[Synonyms]

K3-MNB
Menadione Nicotinamide bisulfite
Menadione nicotinamide bisulfite (MNB)
methyl 1,4-dioxo-2,3-dihydronaphthalene-2-sulfonate,pyridine-3-carboxamide
2-Methyl-1,4-dioxo-1,2,3,4-tetrahydronaphthalene-2-sulfonic acid·3-pyridinecarboxamide
2-Naphthalene sulfonic acid,1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-,compd with 3-pyridinecarboxamide
2-Naphthalene sulfonic acid, 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, compd with 3-pyridinecarboxamide
1,2,3,4-tetrahydro-2-methyl-1,4-dioxonaphthalene-2-sulphonic acid, compound with nicotin-3-amide (1:1)
2-Naphthalenesulfonic acid, 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, compd. with 3-pyridinecarboxamide (1:1)
1,2,3,4-tetrahydro-2-methyl-1,4-dioxonaphthalene-2-sulphonic acid, compound with nicotin-3-amide (1:1) USP/EP/BP
TIANFU-CHEM CAS:73581-79-0 1,2,3,4-tetrahydro-2-methyl-1,4-dioxonaphthalene-2-sulphonic acid, compound with nicotin-3-amide (1:1)
[EINECS(EC#)]

277-543-7
[Molecular Formula]

C11H10O5S.C6H6N2O
[MDL Number]

MFCD16621290
[MOL File]

73581-79-0.mol
[Molecular Weight]

376.38
Chemical PropertiesBack Directory
[Melting point ]

182℃
[InChI]

InChI=1S/C11H10O5S.C6H6N2O/c1-11(17(14,15)16)6-9(12)7-4-2-3-5-8(7)10(11)13;7-6(9)5-2-1-3-8-4-5/h2-5H,6H2,1H3,(H,14,15,16);1-4H,(H2,7,9)
[InChIKey]

DRDSBZXTAXDLDZ-UHFFFAOYSA-N
[SMILES]

C(C1=CN=CC=C1)(=O)N.O=C1C(CC(=O)C2=CC=CC=C12)(C)S(O)(=O)=O
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H410
[Precautionary statements ]

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P273-P391-P501
Hazard InformationBack Directory
[Uses]

Menadione Nicotinamide Bisulfite is also known as Vitamin K3 and is one of 3 synthetic types of Vitamin K along with K4 and K5. Menadione nicotinamide bisulfite is also used as a nutritional supplement for both the prevention of vitamin K deficiency and as a source of supplemental niacin in poultry and swine. Federal regulation 21 CFR 573.625 states that this substance can be added to chicken and turkey feeds at a level not to exceed 2 g per ton of complete feed, and to growing and finishing swine feeds at a level not to exceed 10 g per ton of complete feed.
[Biological Functions]

Menadione nicotinamide bisulphite (MNB) is an animal feed supplement primarily employed to enhance the absorption and utilisation efficiency of nutrients in animal feed, thereby promoting animal growth and development. Additionally, MNB possesses certain immunomodulatory effects, improving animals' disease resistance, promoting the proliferation and differentiation of immune cells, and strengthening the body's immune function.
[Synthesis]

Stabilized vitamin K3 (MNB) was synthesized from menaquinone sodium bisulfite (MSB) and nicotinamide at room temperature. The factors affecting the reaction were examined, and the optimized reaction conditions obtained were: n(MSB): n(nicotinamide)=1:1.5,
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