| Identification | Back Directory | [Name]
kamebakaurin | [CAS]
73981-34-7 | [Synonyms]
Kamebakaurine
kamebakaurin A
KAMEBAKAURINE;KAMEBAKAURIN
Kaur-16-en-15-one, 1,7,14,20-tetrahydroxy-, (1α,7α,14R)- | [Molecular Formula]
C20H30O5 | [MDL Number]
MFCD04974582 | [MOL File]
73981-34-7.mol | [Molecular Weight]
350.45 |
| Chemical Properties | Back Directory | [Melting point ]
232-234℃ | [density ]
1.30±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
4°C, protect from light | [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Kamebakaurin is a natural compound isolated from Rabdosia excisa. Kamebakaurin is a potent inhibitor of NF-κB activation by directly targeting DNA-binding activity of p50[1]. | [storage]
4°C, protect from light | [References]
[1] Lee JH, et al. Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes. J Biol Chem. 2002 May 24;277(21):18411-20. DOI:10.1074/jbc.M201368200 |
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