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7412-78-4

7412-78-4 Structure

7412-78-4 Structure
IdentificationMore
[Name]

GLYCYL-L-GLUTAMIC ACID
[CAS]

7412-78-4
[Synonyms]

BETA-ENDORPHIN (30-31) (HUMAN)
BETA-LIPOTROPIN (88-89) (HUMAN)
BETA-LIPOTROPIN (90-91) (HUMAN)
GLYCYL-L-GLUTAMIC ACID
GLY-GLU
H-GLY-GLU-OH
L-Glutamic acid, N-glycyl-
N-(Aminoacetyl)glutamic acid
N-glycyl-L-glutamic acid
N-glycylglutamic acid
Gly-Glu-OH
Gly-L-Glu-OH
[EINECS(EC#)]

231-019-4
[Molecular Formula]

C7H12N2O5
[MDL Number]

MFCD00008128
[Molecular Weight]

204.18
[MOL File]

7412-78-4.mol
Chemical PropertiesBack Directory
[Melting point ]

155-158 °C (dec.)(lit.)
[Boiling point ]

342.66°C (rough estimate)
[density ]

1.4123 (rough estimate)
[refractive index ]

1.4880 (estimate)
[storage temp. ]

−20°C
[form ]

powder to crystal
[pka]

3.02±0.10(Predicted)
[color ]

White to Almost white
[Water Solubility ]

very faint turbidity
[InChI]

1S/C7H12N2O5/c8-3-5(10)9-4(7(13)14)1-2-6(11)12/h4H,1-3,8H2,(H,9,10)(H,11,12)(H,13,14)/t4-/m0/s1
[InChIKey]

IEFJWDNGDZAYNZ-BYPYZUCNSA-N
[SMILES]

NCC(=O)N[C@@H](CCC(O)=O)C(O)=O
[CAS DataBase Reference]

7412-78-4(CAS DataBase Reference)
Safety DataBack Directory
[Safety Statements ]

S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[HS Code ]

29224985
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. Glycyl-L-glutamic acid doesn’t act directly on AChE synthesis, and may prevent preganglionic neuronal degeneration[1][2].
[Definition]

ChEBI: A dipeptide formed from glycyl and L-glutamic acid residues.
[References]

[1] Koelle GB, et al. Glycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo. Proc DOI:10.1073/pnas.82.15.5213
[2] Yourick JJ, et al. Regeneration of acetylcholinesterase in clonal neuroblastoma-glioma hybrid NG108-15 cells after soman inhibition: effect of glycyl-L-glutamine. Cell Biol Toxicol. 1991 Jul;7(3):229-37. DOI:10.1007/BF00250977
Spectrum DetailBack Directory
[Spectrum Detail]

GLYCYL-L-GLUTAMIC ACID(7412-78-4)MS
GLYCYL-L-GLUTAMIC ACID(7412-78-4)1HNMR
GLYCYL-L-GLUTAMIC ACID(7412-78-4)13CNMR
GLYCYL-L-GLUTAMIC ACID(7412-78-4)IR1
GLYCYL-L-GLUTAMIC ACID(7412-78-4)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Glycyl-L-glutamic acid(7412-78-4)
[Sigma Aldrich]

7412-78-4(sigmaaldrich)
[TCI AMERICA]

Glycyl-L-glutamic Acid(7412-78-4)
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