| Identification | Back Directory | [Name]
N-2-Pyridinyl-1,2-ethanediamine | [CAS]
74764-17-3 | [Synonyms]
NSC 28695
2-(2-PyridylaMino)ethylaMine
N-(2-Pyridinyl)ethylenediaMine
N1-2-pyridinyl-1,2-EthanediaMine
N-(2-AMinoethyl)pyridine-2-aMine
N-Pyridin-2-yl-ethane-1,2-diamine
N1-(pyridin-2-yl)ethane-1,2-diaMine | [Molecular Formula]
C7H11N3 | [MDL Number]
MFCD04039672 | [MOL File]
74764-17-3.mol | [Molecular Weight]
137.19 |
| Chemical Properties | Back Directory | [Appearance]
Light Yellow Oil | [Melting point ]
45-47°C | [Boiling point ]
93-95°C/0.5 Torr | [density ]
1.121±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [pka]
9.19±0.10(Predicted) |
| Hazard Information | Back Directory | [Chemical Properties]
Light Yellow Oil | [Uses]
N-2-Pyridinyl-1,2-ethanediamine is a reactant used in the synthesis of dual histamine H1 and H2 receptor antagonists based on cyanoguanidine. Also used in the synthesis of 2-thiohydantoins as somatostatin receptor ligands, | [Synthesis]
The reaction was carried out with 2-bromopyridine and ethylenediamine with reference to the literature method (11a) to obtain the target product N1-(pyridin-2-yl)ethane-1,2-diamine, which was a light yellow liquid in 85.34% yield. | [References]
[1] Patent: CN105541777, 2016, A. Location in patent: Paragraph 0016; 0077; 0078; 0079
[2] European Journal of Medicinal Chemistry, 1987, vol. 22, p. 91 - 100
[3] Patent: US2002/86850, 2002, A1
[4] Patent: US6610665, 2003, B1
[5] Patent: EP1051425, 2002, B1 |
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DebyeTec.com Inc.
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