ChemicalBook--->CAS DataBase List--->756526-04-2

756526-04-2

756526-04-2 Structure

756526-04-2 Structure
IdentificationBack Directory
[Name]

alpha-aMine-oMega-propionic acid octaethylene glycol
[CAS]

756526-04-2
[Synonyms]

756526-04-2
NH2-PEG8-COOH
NH2-PEG9-acid
H2N-PEG8-COOH
Amino-PEG8-COOH
Amino-PEG8-Acid
AMINE-PEG8-COOH
amino-dPEG 8-acid
H2N-PEG8-CH2CH2COOH
Amino-dPEG(R)8-acid
Amino-PEG8-propionic acid
Amino-PEG8-acid,H2N-PEG8-COOH
α-AMine-ω-propionic acid octaethylene glycol
alpha-aMine-oMega-propionic acid octaethylene glycol
27-Amino-4,7,10,13,16,19,22,25-octaoxaheptacosanoic acid
4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-amino-
3-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
[Molecular Formula]

C19H39NO10
[MDL Number]

MFCD11041146
[MOL File]

756526-04-2.mol
[Molecular Weight]

441.51
Chemical PropertiesBack Directory
[Boiling point ]

547.1±50.0 °C(Predicted)
[density ]

1.128±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

Soluble in Water, DMSO, DCM, DMF
[form ]

solid or viscous liquid
[pka]

4.28±0.10(Predicted)
[color ]

White to light yellow
[InChI]

InChI=1S/C19H39NO10/c20-2-4-24-6-8-26-10-12-28-14-16-30-18-17-29-15-13-27-11-9-25-7-5-23-3-1-19(21)22/h1-18,20H2,(H,21,22)
[InChIKey]

YLKOHZCQTVYVDB-UHFFFAOYSA-N
[SMILES]

C(O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[WGK Germany ]

WGK 3
[HS Code ]

2942000090
[Storage Class]

11 - Combustible Solids
Questions And AnswerBack Directory
[Purity]

>98%
Hazard InformationBack Directory
[Description]

Amino-PEG8-acid is a water soluble PEG linker consisting of an amino group (NH2) with a terminal carboxylic acid. The amine group is reactive with activated NHS esters, carbonyls (ketone, aldehyde) etc.
[Uses]

1-Amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic Acid is used in targeted drug delivery as conjugate with carbon nanotubes. It is also used as linker for enzyme immobilization in optimization of bio-nano interface to enhance enzyme catalytic efficiency.
[General Description]

NH2-PEG8-COOH (also known as Amino-PEG8-Acid, NH2-PEG8-acid CAS 756526-04-2) is a high-purity, monodisperse, water-soluble cross-linking reagent. This compound possesses a primary amine (-NH₂) at one end and a carboxylic acid (-COOH) at the other, linked by a hydrophilic octaethylene glycol spacer. The amine group is highly reactive with activated NHS esters, whilst the carboxyl group can undergo coupling reactions with primary amines via coupling agents such as EDC or HATU.
[reaction suitability]

reagent type: cross-linking reagent
reactivity: carboxyl reactive
[IC 50]

Non-cleavable Linker; PEGs
Spectrum DetailBack Directory
[Spectrum Detail]

alpha-aMine-oMega-propionic acid octaethylene glycol(756526-04-2)1HNMR
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