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76186-04-4

76186-04-4 Structure

76186-04-4 Structure
IdentificationMore
[Name]

(S)-4-ISOPROPYLTHIAZOLIDINE-2-THIONE
[CAS]

76186-04-4
[Synonyms]

(S)-4,5-DIHYDRO-4-ISOPROPYLTHIAZOLE-2-THIOL
(S)-(-)-4-ISOPROPYL-1,3-THIAZOLIDINE-2-THIONE
(S)-4-ISOPROPYL-1,3-THIAZOLIDINE-2-THIONE
(S)-4-ISOPROPYLTHIAZOLIDINE-2-THIONE
2-Thiazolidinethione,4-(1-methylethyl)-,(4S)-(9CI)
[Molecular Formula]

C6H11NS2
[MDL Number]

MFCD03844797
[Molecular Weight]

161.29
[MOL File]

76186-04-4.mol
Chemical PropertiesBack Directory
[Melting point ]

69-71 °C
[Boiling point ]

223.3±23.0 °C(Predicted)
[density ]

1.17±0.1 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[solubility ]

almost transparency in Chloroform
[form ]

powder to crystal
[pka]

12.95±0.40(Predicted)
[color ]

White to Almost white
[optical activity]

[α]20/D -37±3°, c = 1 in chloroform
[CAS DataBase Reference]

76186-04-4(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
[WGK Germany ]

3
[Hazard Note ]

Irritant
[HS Code ]

2934100090
Hazard InformationBack Directory
[Uses]

(S)-4-Isopropylthiazolidine-2-thione may be used as a chiral auxiliary for the stereochemical induction at the phosphorus atom during the diastereoselective synthesis of aryloxy phosphoramidate prodrugs of 3μ-deoxy-2μ,3μ-didehydrothymidine monophosphate (d4TMP).', 'A highly selective and efficient chiral auxiliary which can be directly reduced to its corresponding aldehyde and the chiral auxiliary by reductive cleavage with diisobutylaluminum hydride.
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

76186-04-4(sigmaaldrich)
[TCI AMERICA]

(S)-4-Isopropylthiazolidine-2-thione,>98.0%(GC)(76186-04-4)
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